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Cyclic GMP-Dependent Protein Kinase Type II
Known as:
Cyclic GMP Dependent Protein Kinase Type II
, cGMP-Dependent Protein Kinase 2
, cGMP Dependent Protein Kinase 2
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A cyclic GMP-dependent protein kinase subtype that is expressed predominantly in INTESTINES, BRAIN, and KIDNEY. The protein is myristoylated on its N…
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National Institutes of Health
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In Blood
Process of secretion
antagonists & inhibitors
aspects of radiation effects
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PRKG2 protein, human
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2006
Highly Cited
2006
Cyclic guanosine 5'-monophosphate-dependent protein kinase II is induced by luteinizing hormone and progesterone receptor-dependent mechanisms in granulosa cells and cumulus oocyte complexes of…
V. Sriraman
,
M. Rudd
,
S. Lohmann
,
S. Mulders
,
J. Richards
Molecular endocrinology
2006
Corpus ID: 24358105
Cyclic GMP (cGMP)-dependent protein kinase II (Prkg2, cGK II) was identified as a potential target of the progesterone receptor…
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Highly Cited
1999
Highly Cited
1999
Atrial natriuretic peptide-stimulated Ca2+ reabsorption in rabbit kidney requires membrane-targeted, cGMP-dependent protein kinase type II.
J. Hoenderop
,
A. Vaandrager
,
+6 authors
R. Bindels
Proceedings of the National Academy of Sciences…
1999
Corpus ID: 25200408
Atrial natriuretic peptide (ANP) and nitric oxide (NO) are key regulators of ion and water transport in the kidney. Here, we…
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Highly Cited
1998
Highly Cited
1998
Membrane targeting of cGMP-dependent protein kinase is required for cystic fibrosis transmembrane conductance regulator Cl- channel activation.
A. Vaandrager
,
A. Smolenski
,
+7 authors
H. D. de Jonge
Proceedings of the National Academy of Sciences…
1998
Corpus ID: 24263502
A recently cloned isoform of cGMP-dependent protein kinase (cGK), designated type II, was implicated as the mediator of cGMP…
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Highly Cited
1997
Highly Cited
1997
cGMP Stimulation of Cystic Fibrosis Transmembrane Conductance Regulator Cl− Channels Co-expressed with cGMP-dependent Protein Kinase Type II but Not Type Iβ*
A. Vaandrager
,
B. Tilly
,
+9 authors
H. D. de Jonge
The Journal of Biological Chemistry
1997
Corpus ID: 5830518
In order to investigate the involvement of cGMP-dependent protein kinase (cGK) type II in cGMP-provoked intestinal Cl− secretion…
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Highly Cited
1997
Highly Cited
1997
Endogenous Type II cGMP-dependent Protein Kinase Exists as a Dimer in Membranes and Can Be Functionally Distinguished from the Type I Isoforms*
A. Vaandrager
,
M. Edixhoven
,
+5 authors
H. D. de Jonge
The Journal of Biological Chemistry
1997
Corpus ID: 34564979
In mammalian tissues two types of cGMP-dependent protein kinase (cGK) have been identified. In contrast to the dimeric cGK I, cGK…
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Highly Cited
1996
Highly Cited
1996
Expression of type II cGMP-dependent protein kinase in rat kidney is regulated by dehydration and correlated with renin gene expression.
S. Gambaryan
,
C. Häusler
,
+6 authors
S. Lohmann
The Journal of clinical investigation
1996
Corpus ID: 32758211
cGMP-based regulatory systems are vital for counteracting the renin-angiotensin system (RAS) which promotes volume expansion and…
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Highly Cited
1996
Highly Cited
1996
N-terminal Myristoylation Is Required for Membrane Localization of cGMP-dependent Protein Kinase Type II (*)
A. Vaandrager
,
Erich M. E. Ehlert
,
T. Jarchau
,
S. Lohmann
,
H. D. de Jonge
The Journal of Biological Chemistry
1996
Corpus ID: 4575007
The apical membrane of intestinal epithelial cells harbors a unique isozyme of cGMP-dependent protein kinase (cGK type II) which…
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Highly Cited
1995
Highly Cited
1995
Molecular Characterization of a Type II Cyclic GMP‐Dependent Protein Kinase Expressed in the Rat Brain
A. El-Husseini
,
C. Bladen
,
S. Vincent
Journal of neurochemistry
1995
Corpus ID: 31296046
Abstract: We applied reverse transcription‐PCR to examine the gene expression of cyclic GMP (cGMP)‐dependent protein kinase in…
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Highly Cited
1995
Highly Cited
1995
The Type II Isoform of cGMP-dependent Protein Kinase Is Dimeric and Possesses Regulatory and Catalytic Properties Distinct from the Type I Isoforms (*)
D. Gamm
,
S. Francis
,
T. Angelotti
,
J. Corbin
,
M. Uhler
The Journal of Biological Chemistry
1995
Corpus ID: 42908634
The type I cGMP-dependent protein kinases (cGK Iα and Iβ) form homodimers (subunit Mr ∼ 76,000), presumably through conserved…
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Highly Cited
1994
Highly Cited
1994
Cloning, expression, and in situ localization of rat intestinal cGMP-dependent protein kinase II.
T. Jarchau
,
C. Häusler
,
+5 authors
U. Walter
Proceedings of the National Academy of Sciences…
1994
Corpus ID: 26816966
The cDNA for a membrane-associated cGMP-dependent protein kinase (cGK II) was cloned from rat intestine using reverse…
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