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Cyclic AMP Response Element
Known as:
CRE
, cAMP Response Element
A promoter sequence which interacts with CRE binding proteins to modulate gene expression in response to the level of cAMP in the cell.
National Institutes of Health
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Related topics
2 relations
Chromosomes
promoter
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2007
Highly Cited
2007
1,25-Dihydroxyvitamin D3 Suppresses Renin Gene Transcription by Blocking the Activity of the Cyclic AMP Response Element in the Renin Gene Promoter*
W. Yuan
,
W. Pan
,
+7 authors
Y. Li
Journal of Biological Chemistry
2007
Corpus ID: 45624068
We have shown that 1,25-dihydroxyvitamin D3 (1,25(OH)2D3) down-regulates renin expression. To explore the molecular mechanism, we…
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Highly Cited
2000
Highly Cited
2000
The MAPK/ERK Cascade Targets Both Elk-1 and cAMP Response Element-Binding Protein to Control Long-Term Potentiation-Dependent Gene Expression in the Dentate Gyrus In Vivo
S. Davis
,
P. Vanhoutte
,
C. Pagès
,
J. Caboche
,
S. Laroche
Journal of Neuroscience
2000
Corpus ID: 16269460
The mitogen-activated protein kinase/extracellular signal-regulated kinase (MAPK/ERK) signaling cascade contributes to synaptic…
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Highly Cited
2000
Highly Cited
2000
Rapid and selective induction of BDNF expression in the hippocampus during contextual learning
Jeremy Hall
,
K. Thomas
,
B. Everitt
Nature Neuroscience
2000
Corpus ID: 12072558
The hippocampus is required for many forms of long-term memory in both humans and animals, and formation of long-lasting memories…
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Review
1999
Review
1999
CREB: a stimulus-induced transcription factor activated by a diverse array of extracellular signals.
A. Shaywitz
,
M. Greenberg
Annual Review of Biochemistry
1999
Corpus ID: 31139983
Extracellular stimuli elicit changes in gene expression in target cells by activating intracellular protein kinase cascades that…
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Highly Cited
1998
Highly Cited
1998
Identification of a Signaling Pathway Involved in Calcium Regulation of BDNF Expression
Perry B. Shieh
,
Shu-Ching Hu
,
K. Bobb
,
Tonnis Timmusk
,
Anirvan Ghosh
Neuron
1998
Corpus ID: 5360687
Highly Cited
1994
Highly Cited
1994
Nerve growth factor activates a Ras-dependent protein kinase that stimulates c-fos transcription via phosphorylation of CREB
D. Ginty
,
A. Bonni
,
M. Greenberg
Cell
1994
Corpus ID: 23474145
Highly Cited
1990
Highly Cited
1990
Membrane depolarization and calcium induce c-fos transcription via phosphorylation of transcription factor CREB
M. Sheng
,
Grant McFadden
,
M. Greenberg
Neuron
1990
Corpus ID: 21035353
Highly Cited
1989
Highly Cited
1989
A cluster of phosphorylation sites on the cyclic AMP-regulated nuclear factor CREB predicted by its sequence
G. A. Gonzalez
,
Karen K. Yamamoto
,
+5 authors
M. Montminy
Nature
1989
Corpus ID: 4345950
Cyclic AMP regulates the expression of a number of genes through a conserved promoter element, the CRE1. Moreover, transcrip…
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Highly Cited
1988
Highly Cited
1988
DNA binding activities of three murine Jun proteins: Stimulation by Fos
Y. Nakabeppu
,
K. Ryder
,
D. Nathans
Cell
1988
Corpus ID: 11057487
Highly Cited
1987
Highly Cited
1987
Binding of a nuclear protein to the cyclic-AMP response element of the somatostatin gene
M. Montminy
,
L. Bilezikjian
Nature
1987
Corpus ID: 4345292
Many hormones act on neuroendocrine cells by activating second messenger pathways. Two of these, the phosphoinositol and cAMP…
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