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Cyclic AMP Response Element

Known as: CRE, cAMP Response Element 
A promoter sequence which interacts with CRE binding proteins to modulate gene expression in response to the level of cAMP in the cell.
National Institutes of Health

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Chromosomespromoter

Papers overview

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2016
2016
Resveratrol stimulates cyclic AMP response element mediated gene transcription.
SCOPE Many intracellular effects have been attributed to resveratrol, a polyphenolic phytoalexin found in grapes and in other… 
2005
2005
Prostaglandin E2 drives cyclooxygenase 2 expression via cyclic AMP response element activation in human pancreatic cancer cells
Cyclooxygenase-2 (COX-2) is constitutively expressed in most human primary carcinomas and with its synthesized product… 
Highly Cited
2001
Highly Cited
2001
Hexosamine-induced fibronectin protein synthesis in mesangial cells is associated with increases in cAMP responsive element binding (CREB) phosphorylation and nuclear CREB: the involvement of protein…
Hyperglycemia-induced alterations in mesangial (MES) cell function and extracellular matrix protein accumulation are seen in… 
1997
1997
A GT box element is essential for basal and cyclic adenosine 3',5'-monophosphate regulation of the human surfactant protein A2 gene in alveolar type II cells: evidence for the binding of lung nuclear…
The gene encoding surfactant protein-A (SP-A) is developmentally regulated in type II cells of the fetal lung. In humans there… 
Highly Cited
1996
Highly Cited
1996
Stimulus-transcription Coupling in Pheochromocytoma Cells
To explore stimulus-transcription coupling in pheochromocytoma cells, we studied the biosynthetic response of chromogranin A, the… 
1996
1996
Activation of the Human DNA Polymerase β Promoter by a DNA-alkylating Agent through Induced Phosphorylation of cAMP Response Element-binding Protein-1*
Treatment of cells with the DNA-alkylating agent N-methyl-N′-nitro-N-nitrosoguanidine (MNNG) induces expression of the endogenous… 
Highly Cited
1995
Highly Cited
1995
Calreticulin inhibits vitamin D3 signal transduction.
Calreticulin is a calcium binding protein present primarily in the lumen of the endoplasmic reticulum. However, it can also… 
1993
1993
Presence of a Cyclic AMP Response Element‐Binding Protein in Oligodendrocytes
Abstract: Several lines of evidence indicate that cyclic AMP (cAMP) induces oligodendrocyte differentiation. However, the… 
Highly Cited
1991
Highly Cited
1991
Novel cyclic adenosine 3',5'-monophosphate response element in the human chorionic gonadotropin beta-subunit gene.
CG is encoded by separate alpha- and beta-subunit genes. Expression of both genes is stimulated by cAMP, but the kinetics of… 
Highly Cited
1989
Highly Cited
1989
A cAMP-responsive element regulates expression of the mouse steroid 11 beta-hydroxylase gene.
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