Cyclic AMP Response Element

Known as: CRE, cAMP Response Element 
A promoter sequence which interacts with CRE binding proteins to modulate gene expression in response to the level of cAMP in the cell.
National Institutes of Health

Papers overview

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2008
2008
Genes regulated by cyclic AMP-response element-binding protein (CREB) have been reported to suppress apoptosis, induce cell… (More)
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Highly Cited
2007
Highly Cited
2007
We have shown that 1,25-dihydroxyvitamin D(3) (1,25(OH)(2)D(3)) down-regulates renin expression. To explore the molecular… (More)
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Highly Cited
2007
Highly Cited
2007
Stress regulation of brain-derived neurotrophic factor (BDNF) is implicated in the hippocampal damage observed in depression… (More)
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Highly Cited
2005
Highly Cited
2005
Cyclic AMP response element-binding protein (CREB) is a widely expressed transcription factor whose role in neuronal protection… (More)
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2003
2003
BACKGROUND The balance between apoptosis and proliferation of vascular smooth muscle cells (VSMCs) is believed to contribute to… (More)
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1998
1998
To investigate signaling mechanisms by which hypoxia regulates gene expression, we examined the effect of hypoxia on the cyclic… (More)
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1995
1995
Clinical observations agree that antidepressant drugs are effective only after a lag phase of 1-3 weeks. This delay could be… (More)
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Highly Cited
1992
Highly Cited
1992
Previous studies have implicated adaptations in the cyclic AMP system in mechanisms of opiate tolerance, dependence, and… (More)
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Highly Cited
1989
Highly Cited
1989
Cyclic AMP regulates the expression of a number of genes through a conserved promoter element, the CRE1. Moreover, transcrip… (More)
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Highly Cited
1987
Highly Cited
1987
Many hormones act on neuroendocrine cells by activating second messenger pathways. Two of these, the phosphoinositol and cAMP… (More)
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