Cyclazocine

Known as: 2,6-Methano-3-benzazocin-8-ol, 3-(cyclopropylmethyl)-1,2,3,4,5,6-hexahydro-6,11-dimethyl-, Cyclazocine [Chemical/Ingredient] 
An analgesic with mixed narcotic agonist-antagonist properties.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1965-2015
0102019652015

Papers overview

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1999
1999
(+/-)Cyclazocine, synthesized by Archer in 1962, was originally tested as a treatment for heroin addiction. (+/-)Cyclazocine is a… (More)
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Highly Cited
1995
Highly Cited
1995
The ability of mu-opioid agonists to activate G proteins has been demonstrated by studying the binding of the GTP analogue… (More)
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1986
Highly Cited
1986
The kappa opioid agonists are analgesics that seem to be free of undesired morphine-like effects. Their dysphoric actions… (More)
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1986
1986
The activity of ketocyclazocine, a putative kappa opioid receptor agonist, was studied and compared with that of morphine, a mu… (More)
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1983
1983
There are many similarities in the effects of phencyclidine (PCP) and opioids with sigma agonist activity such as N… (More)
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1981
1981
Separate groups of pigeons were trained to discriminate the IM injection of ketamine, cyclazocine, or dextrorphan from saline… (More)
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1978
1978
In order to characterize the discriminative stimulus properties of cyclazocine squirrel monkeys were trained to discriminate… (More)
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1977
1977
Pentazocine, cyclazocine, and nalorphine are narcotic antagonists that also have analgesic activity of their own. the present… (More)
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Highly Cited
1976
Highly Cited
1976
A series of morphine-like and nalorphine-like drugs were studied in the nondependent, morphine-dependent and cyclazocine… (More)
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1976
1976
Rats were trained to press a lever in order to stimulate their lateral hypothalamus through a chronically implanted electrode… (More)
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