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Cyclazocine

Known as: 2,6-Methano-3-benzazocin-8-ol, 3-(cyclopropylmethyl)-1,2,3,4,5,6-hexahydro-6,11-dimethyl-, Cyclazocine [Chemical/Ingredient] 
An analgesic with mixed narcotic agonist-antagonist properties.
National Institutes of Health

Related topics

Related topics

18 relations

Narrower (7)

8-aminocyclazocine8-carboxamidocyclazocineUM 1046UM-1037

Broader (4)

AnalgesicsAnalgesics, Non-NarcoticAzocinesNarcotic Antagonists
In Bloodagonistsanalogs & derivativesantagonists & inhibitors

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2006
2006
Redefining the structure-activity relationships of 2,6-methano-3-benzazocines. 4. Opioid receptor binding properties of 8-[N-(4'-phenyl)-phenethyl)carboxamido] analogues of cyclazocine and…
The synthesis and evaluation of a series of aryl-containing N-monosubstituted analogues of the lead compound 8… 
2004
2004
Cyclazocine: comparison to hydromorphone and interaction with cocaine
Kappa-opioid agonists produce neurobiological and behavioral effects opposite to those of cocaine and may be useful for the… 
2000
2000
Kappa opioid agonists as targets for pharmacotherapies in cocaine abuse.
1995
1995
Purification, pharmacological characterization and photoaffinity labeling of sigma receptors from rat and bovine brain
Review
1990
Review
1990
Sigma binding sites in the brain; an emerging concept for multiple sites and their relevance for psychiatric disorders.
Highly Cited
1975
Highly Cited
1975
Congenital malformations of the central nervous system produced by narcotic analgesics in the hamster.
1974
1974
The use of cyclazocine in treating narcotic addicts in a low-intervention setting.
This study evaluated the clinical efficacy of cyclazocine when used as part of a direct-service drug-abuse program characterized… 
1973
1973
Measurement of analgesia using a spatial preference test in the rat.
1970
1970
A cyclazocine typology in opiate dependence.
The authors present a typological classification useful in the therapy of opiate dependence based on patients' self-ratings of… 
1968
1968
Clinical studies of cyclazocine in the treatment of narcotic addiction.
Cyclazocine, a long-acting narcotic antagonist, was found to be safe and useful in the treatment of narcotic addicts in a… 
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