Cullin 5 Protein

Known as: CUL-5, Vasopressin-Activated Calcium-Mobilizing Receptor 1, Cullin Homolog 5 
Cullin-5 (780 aa, ~91 kDa) is encoded by the human CUL5 gene. This protein plays a role in both protein ubiquitination and cellular proliferation.
National Institutes of Health

Papers overview

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Highly Cited
2008
Highly Cited
2008
Cullin-RING ligases (CRLs) comprise the largest ubiquitin E3 subclass, in which a central cullin subunit links a substrate… (More)
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Highly Cited
2007
Highly Cited
2007
Many laminated regions of the mammalian brain develop by the migration of neuronal precursor cells, whose final positions are… (More)
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Highly Cited
2006
Highly Cited
2006
Human immunodeficiency virus-1 (HIV-1) Vif overcomes the anti-viral activity of APOBEC3G by targeting it for ubiquitination via a… (More)
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Review
2006
Review
2006
The effect of the pineal indole hormone melatonin on the life span of mice, rats and fruit flies has been studied using various… (More)
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Highly Cited
2005
Highly Cited
2005
Cullin-Ring E3 ubiquitin ligases target substrates for ubiquitin-dependent, proteasome-mediated degradation and regulate critical… (More)
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Highly Cited
2003
Highly Cited
2003
Human immunodeficiency virus-1 (HIV-1) Vif is essential for viral evasion of host antiviral factor CEM15/APOBEC3G. We report that… (More)
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Highly Cited
2003
Highly Cited
2003
Programmed destruction of regulatory proteins through the ubiquitin–proteasome system is a widely used mechanism for controlling… (More)
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Highly Cited
2001
Highly Cited
2001
Although MDM2 plays a major role in regulating the stability of the p53 tumor suppressor protein, other poorly understood MDM2… (More)
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Highly Cited
1999
Highly Cited
1999
Recently we found that NEDD8, a ubiquitin-like protein, was linked covalently to human cullin-4A (abbreviated Cul-4A) by a new… (More)
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1998
1998
Vasopressin is one of several small neuropeptides that are reported to be autocrine growth factors for small cell carcinoma of… (More)
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