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Cosuppression

Known as: Co Suppression, Co-Suppression 
Joint gene silencing of extra copies of genes, such as TRANSGENES, along with the original endogenous gene. Cosuppression is induced by the presence… Expand
National Institutes of Health

Related topics

Related topics

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RNA Interference

Papers overview

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Highly Cited
2011
Highly Cited
2011
Regulation of somatic cell reprogramming through inducible mir-302 expression
Global demethylation is required for early zygote development to establish stem cell pluripotency, yet our findings reiterate… Expand
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Review
2005
Review
2005
Non-coding RNAs: new players in eukaryotic biology.
The completion of the human, mouse and other eukaryotic genomes were important scientific milestones, but they were just small… Expand
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Highly Cited
2004
Highly Cited
2004
Identification and genetic analysis of normal and mutant phytoene synthase genes of tomato by sequencing, complementation and co-suppression
A tomato phytoene synthase gene, Psyl, has recently been isolated as the clone GTOM5 [20] and shown by sequence identity to be… Expand
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Highly Cited
2001
Highly Cited
2001
Construct design for efficient, effective and high-throughput gene silencing in plants.
Post-transcriptional silencing of plant genes using anti-sense or co-suppression constructs usually results in only a modest… Expand
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Highly Cited
2001
Highly Cited
2001
Non‐coding RNAs: the architects of eukaryotic complexity
Around 98% of all transcriptional output in humans is non‐coding RNA. RNA‐mediated gene regulation is widespread in higher… Expand
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Review
2001
Review
2001
Post-transcriptional gene silencing in plants.
Post-transcriptional gene silencing (PTGS) in plants is an RNA-degradation mechanism that shows similarities to RNA interference… Expand
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Highly Cited
1999
Highly Cited
1999
Gene silencing in Neurospora crassa requires a protein homologous to RNA-dependent RNA polymerase
In plants and fungi, the introduction of transgenes can lead to post-transcriptional gene silencing,. This phenomenon, in which… Expand
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Highly Cited
1997
Highly Cited
1997
Systemic acquired silencing: transgene‐specific post‐transcriptional silencing is transmitted by grafting from silenced stocks to non‐silenced scions
Using grafting procedures, we investigated the transmission of co‐suppression of nitrate reductase and nitrite reductase host… Expand
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Highly Cited
1990
Highly Cited
1990
Introduction of a Chimeric Chalcone Synthase Gene into Petunia Results in Reversible Co-Suppression of Homologous Genes in trans.
We attempted to overexpress chalcone synthase (CHS) in pigmented petunia petals by introducing a chimeric petunia CHS gene… Expand
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Review
1990
Review
1990
Altered gene expression in plants due to trans interactions between homologous genes.
We have attempted to explain co-suppression in terms of a hypothesis whereby homologous sequences are able to interact… Expand
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