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Corticotropin Receptors

Known as: Receptors, Corticotropin, Receptors, ACTH, Receptors, Adrenocorticotropic Hormone 
Cell surface receptors that bind CORTICOTROPIN; (ACTH, adrenocorticotropic hormone) with high affinity and trigger intracellular changes… 
National Institutes of Health

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CorticotropinIn BloodMC2R geneagonists

Papers overview

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Highly Cited
2008
Highly Cited
2008
The melanocortin 2 receptor accessory protein exists as a homodimer and is essential for the function of the melanocortin 2 receptor in the mouse y1 cell line.
The ACTH receptor [melanocortin 2 receptor (MC2R)] gene produces a functional receptor only when transfected into cells of… 
Highly Cited
2003
Highly Cited
2003
Effects of postischemic environment on transcription factor and serotonin receptor expression after permanent focal cortical ischemia in rats
Review
2001
Review
2001
ACTH-receptor expression, regulation and role in adrenocortial tumor formation.
The regulation of the ACTH-receptor gene is unique in that it is up-regulated by its own ligand, ACTH. Ligand-induced up… 
Highly Cited
1998
Highly Cited
1998
25-Hydroxycholesterol is not a ligand for the orphan nuclear receptor steroidogenic factor-1 (SF-1).
The orphan nuclear receptor steroidogenic factor-1 (SF-1) is involved in the transcriptional regulation of all the steroid… 
Review
1996
Review
1996
Defects in G protein-coupled signal transduction in human disease.
G proteins couple receptors for many hormones and neurotransmitters to effectors that regulate second messenger metabolism. G… 
Review
1996
Review
1996
Receptor biology of the melanocortins, a family of neuroimmunomodulatory peptides.
Melanocortins, melanocyte-stimulating hormones (MSH) and adrenocorticotropic hormone (ACTH) are homologous natural peptides… 
Highly Cited
1994
Highly Cited
1994
Mutations of the ACTH receptor gene are only one cause of familial glucocorticoid deficiency.
Familial glucocorticoid deficiency (FGD) is an autosomal recessive syndrome of failure of adrenal cortisol responsiveness to… 
Highly Cited
1993
Highly Cited
1993
Functional characterization of the cloned human ACTH receptor: impaired responsiveness of a mutant receptor in familial glucocorticoid deficiency.
The putative ACTH receptor gene has been identified on the basis of its tissue specific expression, structure, and limited… 
Highly Cited
1974
Highly Cited
1974
5'-Guanylylimidodiphosphate, a potent activator of adenylate cyclase systems in eukaryotic cells.
5'-Guanylylimidodiphosphate (Gpp(NH)-p) stimulates adenylate cyclase [ATP-pyrophosphate-lyase (cyclizing), EC 4.6.1.1] activity… 
Highly Cited
1971
Highly Cited
1971
Inhibition of replication in functional mouse adrenal tumor cells by adrenocorticotropic hormone mediated by adenosine 3':5'-cyclic monophosphate.
Adrenocorticotropic hormone (ACTH) inhibited replication in functional adrenal tumor cells with a concomitant stimulation of… 
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