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Copper Cu 62 Ethylglyoxal Bis(thiosemicarbazone)

Known as: 62Cu-ETS, 62Cu-Ethylglyoxal Bis, 62Cu-Ethylglyoxal Bis(thiosemicarbazone) 
A radiopharmaceutical composed of the nonspecific perfusion agent ethylglyoxal bis(thiosemicarbazone) (ETS) linked to the beta-emitting, radioisotope… 
National Institutes of Health

Papers overview

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2011
2011
Novel bis(thiosemicarbazones) of the 3,5-diacetyl-1,2,4-triazol series and their platinum(II) complexes: chemistry, antiproliferative activity and preliminary nephrotoxicity studies.
The preparation and characterization of three novel (4)N-monosubstituted bis(thiosemicarbazone) ligands of 3,5-diacetyl-1,2,4… 
2007
2007
Assessment of Cu-ETS as a PET radiopharmaceutical for evaluation of regional renal perfusion.
Highly Cited
2004
Highly Cited
2004
Acetylacetonate bis(thiosemicarbazone) complexes of copper and nickel: towards new copper radiopharmaceuticals.
A series of copper(II) and nickel(II) 1,3-bis(thiosemicarbazonato) complexes have been synthesised by the reaction of the metal… 
1995
1995
Species-dependent binding of copper(II) bis(thiosemicarbazone) radiopharmaceuticals to serum albumin.
UNLABELLED Copper-62-labeled pyruvaldehyde bis(N4-methylthiosemicarbazonato)-copper(II) (Cu-PTSM) is a generator-based PET… 
Highly Cited
1990
Highly Cited
1990
Structure-activity relationships for metal-labeled blood flow tracers: comparison of keto aldehyde bis(thiosemicarbazonato)copper(II) derivatives.
Radiocopper-labeled pyruvaldehyde bis(N4-methylthiosemicarbazonato)copper(II), Cu[PTSM], is under investigation as a… 
Highly Cited
1988
Highly Cited
1988
Polyamines and insulin production in isolated mouse pancreatic islets.
The aim of the present study was to evaluate the role of polyamines in the metabolism and insulin production of pancreatic-islet… 
1984
1984
Physiological effects in bovine lymphocytes of inhibiting polyamine synthesis with ethylglyoxal bis(guanylhydrazone).
Previous results have suggested that ethylglyoxal bis(guanylhydrazone) is a more specific inhibitor of polyamine biosynthesis… 
Highly Cited
1980
Highly Cited
1980
Transition series metals and sulfhydryl reagents induce the synthesis of four proteins in eukaryotic cells.
1967
1967
Metabolic Effects of Copper in Intact Cells: Comparative Activity of Cupric Chloride and the Cupric Chelate of Kethoxal Bis(thiosemicarbazone)
The exposure of sarcoma 180 ascites cells to the cupric chelate [Cu(II)KTS] of kethoxal bis(thiosemicarbazone) (KTS) resulted in… 
1967
1967
Inhibition of the growth of sarcoma 180 ascites cells by combinations of inhibitors of nucleic acid biosynthesis and the cupric chelate of kethoxal bis-(thiosemicarbazone).
The tumor-inhibitory potency of combinations of the cupric chelate of kethoxal bis(thiosemicarbazone) [Cu(II)KTS] with several… 
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