Conventional (Clear Cell) Renal Cell Carcinoma

Known as: Conventional (Clear Cell) Renal Cell Adenocarcinoma, Hypernephroid Carcinoma, Hypernephromas 
A malignant epithelial neoplasm of the kidney characterized by the presence of lipid-containing clear cells within a vascular network. The tumor may… (More)
National Institutes of Health

Papers overview

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Review
2017
Review
2017
Importance Girentuximab is a chimeric monoclonal antibody that binds carbonic anhydrase IX, a cell surface glycoprotein… (More)
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Highly Cited
2014
Highly Cited
2014
Clear cell renal carcinomas (ccRCCs) can display intratumor heterogeneity (ITH). We applied multiregion exome sequencing (M-seq… (More)
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Highly Cited
2009
Highly Cited
2009
MicroRNA regulate mRNA levels in a tissue specific way, either by inducing degradation of the transcript or by inhibiting… (More)
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Highly Cited
2008
Highly Cited
2008
Highly Cited
2008
von Hippel-Lindau (VHL) tumor suppressor loss results in hypoxia-inducible factor alpha (HIF-alpha) stabilization and occurs in… (More)
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Highly Cited
2007
Highly Cited
2007
BACKGROUND We conducted a phase 3, randomized, double-blind, placebo-controlled trial of sorafenib, a multikinase inhibitor of… (More)
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Highly Cited
2006
Highly Cited
2006
CONTEXT Current treatment options for metastatic renal cell carcinoma (RCC) are limited and there is a need to identify novel and… (More)
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Highly Cited
2003
Highly Cited
2003
BACKGROUND The objective of the current study was to develop an algorithm to predict progression to metastases after radical… (More)
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Highly Cited
2002
Highly Cited
2002
PURPOSE Currently outcome prediction in renal cell carcinoma is largely based on pathological stage and tumor grade. We developed… (More)
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Highly Cited
2001
Highly Cited
2001
To better understand the molecular mechanisms that underlie the tumorigenesis and progression of clear cell renal cell carcinoma… (More)
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