Congenic Strain

Congenic strains are produced by transferring a mutation from one genetic background to a specific inbred strain through repeated backcrossing. The… (More)
National Institutes of Health

Papers overview

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2015
2015
Mucosal-associated invariant T cells (MAITs) have potent antimicrobial activity and are abundant in humans (5%-10% in blood… (More)
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2004
2004
At least 20 insulin-dependent diabetes (Idd) loci modify the progression of autoimmune diabetes in the NOD mouse, an animal model… (More)
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2004
2004
Linkage studies have identified many chromosomal regions containing obesity genes in mice. However, only a few of these… (More)
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2003
2003
Human essential hypertension is a complex polygenic trait with underlying genetic components that remain unknown. The stroke… (More)
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Highly Cited
1998
Highly Cited
1998
An F2 population (n = 151) derived from Dahl salt-sensitive (S) and Lewis rats was raised on a 8% NaCl diet for 9 weeks and… (More)
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1998
1998
Previously we presented suggestive evidence from an F2 segregating population for an interaction on blood pressure (BP) between… (More)
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Highly Cited
1997
Highly Cited
1997
The 129 mouse is the most widely used strain in gene targeting experiments. However, numerous substrains exist with demonstrable… (More)
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Highly Cited
1995
Highly Cited
1995
To examine whether mtDNA is uni- or biparentally transmitted in mice, we developed an assay that can detect sperm mtDNA in a… (More)
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Highly Cited
1994
Highly Cited
1994
Insulin-dependent diabetes mellitus (IDDM) in NOD/Lt mice represents a complex polygenic disease. NOR/Lt is a recombinant… (More)
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Highly Cited
1973
Highly Cited
1973
A new congenic strain of obese mice, C57BK/KsJ-ob, has been developed for comparison with the C57BL/6J-ob congenic strain. While… (More)
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