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Combinatorial chemistry
Known as:
High-throughput chemistry
, Combinational chemistry
, Combinatorial libraries
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Combinatorial chemistry comprises chemical synthetic methods that make it possible to prepare a large number (tens to thousands or even millions) of…
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Related topics
Related topics
17 relations
Biochip
Chemical library
Chemical space
Chirality (chemistry)
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Broader (1)
Cheminformatics
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2008
2008
Cu-Catalyzed Formation of Triazole-Linked Glycoamino Acids and Application in Chemoenzymatic Peptide Synthesis
Brian H. M. Kuijpers
,
S. Groothuys
,
+5 authors
F. Rutjes
2008
Corpus ID: 207671790
Novel stable triazole-linked glycoamino acids have been prepared, with the heterocyclic moiety being established by efficient Cu…
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Review
2005
Review
2005
Flow Injection-Capillary Electrophoresis (FI-CE): Recent Advances and Applications
G. Hanrahan
,
Froseen Dahdouh
,
Keith Clarke
,
F. Gomez
2005
Corpus ID: 20558625
This paper presents a comprehensive review of how recent advances in flow injection-capillary electrophoresis (FI-CE) technology…
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2005
2005
A deterministic annealing approach to combinatorial library design for drug discovery
P. Sharma
,
S. Salapaka
,
Carolyn L. Beck
Proceedings of the , American Control Conference…
2005
Corpus ID: 3223045
In this paper we propose a new algorithm for the design of a lead generation library for the purpose of drug discovery. The…
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Highly Cited
2003
Highly Cited
2003
Combinatorial Chemistry: Synthesis and Application
Stephen R. Wilson
,
A. Czarnik
2003
Corpus ID: 92235934
Partial table of contents: Parallel Organic Synthesis Using Parke-Davis Diversomer Technology (S. DeWitt & A. Czarnik). Polymer…
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2003
2003
Combinatorial chemistry and the Grid
J. Frey
,
M. Bradley
,
+7 authors
A. Welsh
2003
Corpus ID: 57408657
Chemistry has always made extensive use of the developing computing technology and available computing power though activities…
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2003
2003
Context Slicing the Chemical Aether
J. Frey
,
D. D. Roure
,
+6 authors
Terry R. Payne
2003
Corpus ID: 18897114
In this paper we discuss the information system requirements of an e-Science scenario, drawn from chemistry research, and…
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1999
1999
Reactivity Prediction Models Applied to the Selection of Novel Candidate Building Blocks for High-Throughput Organic Synthesis of Combinatorial Libraries
Mircea Braban
,
I. Pop
,
Xavier Willard
,
D. Horvath
Journal of chemical information and computer…
1999
Corpus ID: 23597476
Quantitative structure−property relationships (QSPRs) expressing the reactivity of compounds on the basis of molecular…
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1998
1998
Selection of phage display combinatorial library peptides with affinity for a yohimbine imprinted methacrylate polymer
J. Berglund
,
C. Lindbladh
,
I. Nicholls
,
K. Mosbach
1998
Corpus ID: 16381511
α2-Adrenoreceptor mimics, prepared by molecular imprinting of yohimbine, were used to select ligands from a phage display…
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1998
1998
Structure-based inhibitor design for CDK2, a cell cycle controlling protein kinase
Sung-Hou Kim
,
E. Lawrence
1998
Corpus ID: 86593805
Abstract
1997
1997
Combinatorial Libraries on Rigid Scaffolds: Solid Phase Synthesis of Variably Substituted Pyrazoles and Isoxazoles
A. Marzinzik
,
E. Felder
1997
Corpus ID: 6214809
Author to whom correspondence should be addressed. Present address: Pharmaceuticals Division, Core Drug DiscoveryTechnologies…
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