Clustered Regularly Interspaced Short Palindromic Repeats

Known as: Sequences, CRISPR, CRISPR Sequence, Elements, CRISPR 
Repetitive nucleic acid sequences that are principal components of the archaeal and bacterial CRISPR-CAS SYSTEMS, which function as adaptive… (More)
National Institutes of Health

Related topics

Related topics

6 relations
CRISPR LociCRISPR-Associated ProteinsCRISPR-Cas Lociaspects of radiation effects
(More)

Narrower (1)

CRISPR Spacers

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2017
Review
2017
Progress and prospects in plant genome editing
The emergence of sequence-specific nucleases that enable genome editing is revolutionizing basic and applied biology. Since the… (More)
  • figure 1
  • figure 2
  • figure 3
Is this relevant?
Highly Cited
2015
Highly Cited
2015
Harnessing the clustered regularly interspaced short palindromic repeat (CRISPR)/CRISPR-associated Cas9 system to disrupt the hepatitis B virus
The current therapies to treat hepatitis B virus (HBV) infection are limited. Recently, clustered regularly interspaced short… (More)
  • figure 1
  • figure 2
  • figure 5
  • figure 3
  • figure 6
Is this relevant?
Highly Cited
2011
Highly Cited
2011
Mature clustered, regularly interspaced, short palindromic repeats RNA (crRNA) length is measured by a ruler mechanism anchored at the precursor processing site.
Precise RNA processing is fundamental to all small RNA-mediated interference pathways. In prokaryotes, clustered, regularly… (More)
Is this relevant?
Highly Cited
2011
Highly Cited
2011
Interference by clustered regularly interspaced short palindromic repeat (CRISPR) RNA is governed by a seed sequence.
Prokaryotic clustered regularly interspaced short palindromic repeat (CRISPR)/Cas (CRISPR-associated sequences) systems provide… (More)
  • figure 1
  • figure 2
  • figure 3
Is this relevant?
Review
2011
Review
2011
Clustered regularly interspaced short palindromic repeats (CRISPRs): the hallmark of an ingenious antiviral defense mechanism in prokaryotes.
Many prokaryotes contain the recently discovered defense system against mobile genetic elements. This defense system contains a… (More)
  • figure 1
  • table 1
  • figure 2
  • figure 3
Is this relevant?
Highly Cited
2011
Highly Cited
2011
Structural and functional characterization of an archaeal clustered regularly interspaced short palindromic repeat (CRISPR)-associated complex for antiviral defense (CASCADE).
In response to viral infection, many prokaryotes incorporate fragments of virus-derived DNA into loci called clustered regularly… (More)
Is this relevant?
Highly Cited
2008
Highly Cited
2008
A novel family of sequence-specific endoribonucleases associated with the clustered regularly interspaced short palindromic repeats.
Clustered regularly interspaced short palindromic repeats (CRISPRs) together with the associated CAS proteins protect microbial… (More)
Is this relevant?
Highly Cited
2007
Highly Cited
2007
CRISPRFinder : a web tool to identify clustered regularly interspaced short palindromic repeats
Clustered regularly interspaced short palindromic repeats (CRISPRs) constitute a particular family of tandem repeats found in a… (More)
  • figure 1
  • figure 2
Is this relevant?
Highly Cited
2006
Highly Cited
2006
CRISPR Recognition Tool (CRT): a tool for automatic detection of clustered regularly interspaced palindromic repeats
Clustered Regularly Interspaced Palindromic Repeats (CRISPRs) are a novel type of direct repeat found in a wide range of bacteria… (More)
  • figure 1
  • figure 2
  • figure 2
  • table 1
Is this relevant?
Highly Cited
2005
Highly Cited
2005
Clustered regularly interspaced short palindrome repeats (CRISPRs) have spacers of extrachromosomal origin.
Numerous prokaryote genomes contain structures known as clustered regularly interspaced short palindromic repeats (CRISPRs… (More)
  • table 1
  • figure 1
  • figure 2
  • figure 3
  • table 2
Is this relevant?