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Clioquinol

Known as: Iodochlorhydroxyquin, Iodochlorhydroxyquinoline, Iodochloroxyquinoline 
An orally bioavailable, lipophilic, copper-binding, halogenated 8-hydroxyquinoline with antifungal, antiparasitic and potential antitumor activities… Expand
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
The antifungal and amoebicidal drug clioquinol (CQ) was withdrawn from the market when it was linked to an epidemic of subacute… Expand
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Highly Cited
2008
Highly Cited
2008
As a disease-modifying approach for Alzheimer's disease (AD), clioquinol (CQ) targets beta-amyloid (Abeta) reactions with… Expand
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Highly Cited
2007
Highly Cited
2007
There is a growing body of evidence to support a role for oxidative stress in Alzheimer's disease (AD), with increased levels of… Expand
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Highly Cited
2005
Highly Cited
2005
IntroductionA physiological feature of many tumor tissues and cells is the tendency to accumulate high concentrations of copper… Expand
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Highly Cited
2005
Highly Cited
2005
In investigating the role of metal ions in the pathogenesis of Huntington's disease, we examined the effects of clioquinol, a… Expand
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Highly Cited
2005
Highly Cited
2005
Clioquinol, a metal chelator, has been used for many years as an antimicrobial agent and more recently as a potential treatment… Expand
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Highly Cited
2004
Highly Cited
2004
Clioquinol, a 8-hydroxyquinoline derivative, is producing very encouraging results in the treatment of Alzheimer's disease (AD… Expand
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Highly Cited
2003
Highly Cited
2003
BACKGROUND Alzheimer disease (AD) may be caused by the toxic accumulation of beta-amyloid (Abeta). OBJECTIVE To test this… Expand
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Review
2003
Review
2003
The cause of Alzheimer's disease (AD) is closely related to the aggregation of a normal protein, beta-amyloid (Abeta), within the… Expand
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Highly Cited
2001
Highly Cited
2001
Inhibition of neocortical beta-amyloid (Abeta) accumulation may be essential in an effective therapeutic intervention for… Expand
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