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Clioquinol

Known as: Iodochlorhydroxyquin, Iodochlorhydroxyquinoline, Iodochloroxyquinoline 
An orally bioavailable, lipophilic, copper-binding, halogenated 8-hydroxyquinoline with antifungal, antiparasitic and potential antitumor activities… 
National Institutes of Health

Related topics

Related topics

26 relations
AllergensBetamethasone / ClioquinolClioquinol 30 MG/ML / Hydrocortisone 5 MG/ML Topical Cream [Dermasorb AF]Hypersensitivity

Narrower (12)

ChinoformEntero-SeptolEntero-VioformEnterum

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2017
Highly Cited
2017
Novel mitochondria targeted copper(ii) complexes of ferrocenyl terpyridine and anticancer active 8-hydroxyquinolines showing remarkable cytotoxicity, DNA and protein binding affinity.
Metal complexes with organelle specificity and potent but selective cytotoxicity are highly desirable. In this work, we report… 
Highly Cited
2011
Highly Cited
2011
Hydroxyquinoline based binders: promising ligands for chelatotherapy?
Highly Cited
2011
Highly Cited
2011
Methylaluminium 8-quinolinolates: synthesis, characterization and use in ring-opening polymerization (ROP) of ε-caprolactone.
The stoichiometric reactions of 2-(2,6-R-phenylimino)quinolin-8-ol (L1-L5, L1: R = Me, L2: R = Et, L3: R = (i)Pr, L4: R = Cl, L5… 
Review
2009
Review
2009
Brain proteins that mind metals: a neurodegenerative perspective.
There are numerous neurodegenerative diseases but Alzheimer's disease and Parkinson's disease are the most common. In contrast… 
Highly Cited
2009
Highly Cited
2009
The Anti-neurodegeneration Drug Clioquinol Inhibits the Aging-associated Protein CLK-1*
The development of neurodegenerative diseases such as Alzheimer, Parkinson, and Huntington disease is strongly age-dependent… 
Highly Cited
2008
Highly Cited
2008
Carbonic anhydrase inhibitors: Inhibition of the new membrane-associated isoform XV with phenols.
Highly Cited
2006
Highly Cited
2006
Clioquinol and docosahexaenoic acid act synergistically to kill tumor cells
Clioquinol, an 8-hydroxyquinoline derivative (5-chloro-7-iodo-8-hydroxyquinoline) with antimicrobial properties, has recently… 
Review
2000
Review
2000
Subacute myelo‐optico‐neuropathy: Clioquinol intoxication in humans and animals
It remains a tragic event that some 10 000 individuals in Japan developed a unique neurologic disease, subacute myelo‐optico… 
Review
1995
Review
1995
The prevention of nickel contact dermatitis
Chelating agents and other substances can be used to bind nickel or reduce its penetration through the skin, and hence to reduce… 
1973
1973
Pharmacokinetics of iodochlorhydroxyquin in man.
Abstract A method of extracting iodochlorhydroxyquin from plasma and quantitating by GLC was developed and used to study the… 
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