FAQ

Clearing Agent

Any substance that is administered to facilitate the removal of another substance.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1944-2017
051019442016

Papers overview

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2016
2016
Super-Resolution Mapping of Neuronal Circuitry With an Index-Optimized Clearing Agent.
Super-resolution imaging deep inside tissues has been challenging, as it is extremely sensitive to light scattering and spherical… (More)
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2015
2015
A versatile clearing agent for multi-modal brain imaging
Extensive mapping of neuronal connections in the central nervous system requires high-throughput µm-scale imaging of large… (More)
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Highly Cited
2013
Highly Cited
2013
SeeDB: a simple and morphology-preserving optical clearing agent for neuronal circuit reconstruction
We report a water-based optical clearing agent, SeeDB, which clears fixed brain samples in a few days without quenching many… (More)
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2008
2008
Optical clearing of human skin: comparative study of permeability and dehydration of intact and photothermally perforated skin.
Accelerated diffusion of water and hyperosmotic optical clearing agents is studied as a result of enhanced epidermal permeability… (More)
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2006
2006
Using sandpaper for noninvasive transepidermal optical skin clearing agent delivery.
We present a gentle mechanical method for the noninvasive transepidermal delivery of topically applied optical skin clearing… (More)
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2005
2005
Enhancement of transepidermal skin clearing agent delivery using a 980 nm diode laser.
BACKGROUND AND OBJECTIVES Patient compliant optical skin clearing requires non-invasive topical delivery of clearing agents such… (More)
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2004
2004
Optical clearing of in vivo human skin: implications for light-based diagnostic imaging and therapeutics.
The complex morphological nature of human skin provides a highly scattering medium for visible and nearinfrared wavelengths due… (More)
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Highly Cited
2000
Highly Cited
2000
Phase II trial of yttrium-90-DOTA-biotin pretargeted by NR-LU-10 antibody/streptavidin in patients with metastatic colon cancer.
A Phase II study of yttrium-90-tetra-azacyclododecanetetra-acetic acid-biotin (90Y-DOTA-biotin) pretargeted by NR-LU-10 antibody… (More)
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1996
1996
Polyethylene glycol modification of a galactosylated streptavidin clearing agent: effects on immunogenicity and clearance of a biotinylated anti-tumour antibody.
Effective radioimmunotherapy is limited by slow antibody clearance from the circulation, which results in low tumour to blood… (More)
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1984
1984
Mayer's hemalum-methyl salicylate: a stain-clearing technique for observations within whole ovules.
Nondissected ovaries of tuber-bearing Solanum sp. were stained with Mayer's hemalum, a positive stain for chromatin and nucleoli… (More)
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