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Clearing Agent

Any substance that is administered to facilitate the removal of another substance.
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2013
Highly Cited
2013
Diels–Alder Reaction for Tumor Pretargeting: In Vivo Chemistry Can Boost Tumor Radiation Dose Compared with Directly Labeled Antibody
Current pretargeting systems use noncovalent biologic interactions, which are prone to immunogenicity. We previously developed a… Expand
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2010
2010
A physical method to enhance transdermal delivery of a tissue optical clearing agent: Combination of microneedling and sonophoresis
Various physical methods, such as microneedling, laser ablation, sonophoresis, and sandpaper, have been widely studied to enhance… Expand
2006
2006
Effect of optical tissue clearing on spatial resolution and sensitivity of bioluminescence imaging.
In vivo bioluminescence imaging (BLI) is a powerful method of in vivo molecular imaging based on the use of optically active… Expand
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Highly Cited
2006
Highly Cited
2006
Using sandpaper for noninvasive transepidermal optical skin clearing agent delivery.
We present a gentle mechanical method for the noninvasive transepidermal delivery of topically applied optical skin clearing… Expand
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Highly Cited
2005
Highly Cited
2005
Enhancement of transepidermal skin clearing agent delivery using a 980 nm diode laser
Patient compliant optical skin clearing requires non‐invasive topical delivery of clearing agents such as glycerol. This requires… Expand
Highly Cited
2003
Highly Cited
2003
Comparison of anti-CD20 and anti-CD45 antibodies for conventional and pretargeted radioimmunotherapy of B-cell lymphomas.
Radiolabeled anti-CD20 antibodies produce responses in 60% to 95% of patients with relapsed non-Hodgkin lymphoma (NHL); however… Expand
Highly Cited
1996
Highly Cited
1996
Polyethylene glycol modification of a galactosylated streptavidin clearing agent: effects on immunogenicity and clearance of a biotinylated anti-tumour antibody.
Effective radioimmunotherapy is limited by slow antibody clearance from the circulation, which results in low tumour to blood… Expand
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Highly Cited
1984
Highly Cited
1984
Mayer's hemalum-methyl salicylate: a stain-clearing technique for observations within whole ovules.
Nondissected ovaries of tuber-bearing Solanum sp. were stained with Mayer's hemalum, a positive stain for chromatin and nucleoli… Expand
1983
1983
Steroid-induced femoral head pressure changes and their response to lipid-clearing agents.
In rabbits, cortisone increases marrow fat cell size and intrafemoral head pressure, produces systemic fatty embolization, and… Expand
Highly Cited
1964
Highly Cited
1964
A Method for Studying the External Anatomy of Copepods
We have found lactic acid to be the best clearing agent for the preparation of temporary mounts of whole or dissected copepods… Expand
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