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There are numerous ways that endocytic cargo molecules may be internalized from the surface of eukaryotic cells. In addition to… Expand The internalization of various cargo proteins and lipids from the mammalian cell surface occurs through the clathrin and lipid… Expand Plasma membrane receptors can be endocytosed through clathrin-dependent and clathrin-independent pathways. Here, we show that the… Expand Non-phagocytic eukaryotic cells can internalize particles <1 microm in size, encompassing pathogens, liposomes for drug delivery… Expand Clathrin-coated vesicles carry traffic from the plasma membrane to endosomes. We report here the real-time visualization of cargo… Expand Clathrin-mediated endocytosis involves cargo selection and membrane budding into vesicles with the aid of a protein coat… Expand The importance of cholesterol for endocytosis has been investigated in HEp-2 and other cell lines by using methyl-beta… Expand Epidermal growth factor receptor (EGFR) signaling was analyzed in mammalian cells conditionally defective for receptor-mediated… Expand Tyrosine-based signals within the cytoplasmic domain of integral membrane proteins mediate clathrin-dependent protein sorting in… Expand The clathrin-coated pit lattice is held onto the plasma membrane by an integral membrane protein that binds the clathrin AP-2… Expand