Ciliary Neurotrophic Factor
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Neurotrophic factors are agents with a promising ability to retard progression of neurodegenerative diseases and are effective in… Expand Soluble and membrane embedded neurotrophic factors bind to specific receptors on responsive neurons and thereby initiate dramatic… Expand A comparison was made of the permeabilities of different neurotrophic factors at the blood-brain barrier (BBB) and blood-nerve… Expand The signaling mechanisms that control the survival of CNS neurons are poorly understood. Here we show that, in contrast to PNS… Expand After transection of the optic nerve (ON) in adult rats, retinal ganglion cells (RGC) progressively degenerate until, after two… Expand CILIARY neurotrophic factor (CNTF) supports the survival of embryonic motor neurons in vitro1,2 and in vivo3, and prevents lesion… Expand In previous studies, it has been demonstrated that ciliary neurotrophic factor (CNTF) has a potent survival effect on various… Expand THE period of natural cell death in the development of rodent motor neurons is followed by a period of sensitivity to axonal… Expand CILIARY neurotrophic factor (CNTF) was originally characterized as a survival factor for chick ciliary neurons in vitro1. More… Expand Ciliary neurotrophic factor (CNTF) is one of a small number of proteins with neurotrophic activities distinct from nerve growth… Expand