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Chymotrypsin-Like Elastase Family Member 1, human

Known as: Pancreatic Elastase 1, Elastase 1, Chymotrypsin-Like Elastase Family Member 1 
Chymotrypsin-like elastase family member 1 (258 aa, ~28 kDa) is encoded by the human CELA1 gene. This protein is involved in protein hydrolysis.
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
Diabet. Med. 29, 1047–1054 (2012) 
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2010
2010
IntroductionOur objective was to measure human stool elastase-1 to determine the effect of distal pancreatectomy on exocrine… Expand
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Highly Cited
2004
Highly Cited
2004
OBJECTIVE To test the hypothesis that some patients with cystic fibrosis (CF) are misclassified as pancreatic insufficient, using… Expand
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Highly Cited
2003
Highly Cited
2003
BackgroundA progressive decline in pancreatic function is possible in cystic fibrosis (CF) patients with exocrine pancreatic… Expand
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Highly Cited
2001
Highly Cited
2001
BACKGROUND Tubeless pancreatic function tests measuring the content of elastase-1 and the activity of chymotrypsin in stool are… Expand
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Highly Cited
2000
Highly Cited
2000
Abstract Reduced exocrine pancreatic function has been observed in a high percentage of patients with type 1 diabetes in the past… Expand
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Highly Cited
1999
Highly Cited
1999
BACKGROUND The secretin-cholecystokinin (CCK) test is the gold standard in the evaluation of exocrine pancreatic insufficiency… Expand
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Highly Cited
1998
Highly Cited
1998
We studied potential indicators of severe acute pancreatitis by measuring the blood concentrations of various cytokines… Expand
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Highly Cited
1997
Highly Cited
1997
Fecal elastase-1 is a candidate for a sensitive noninvasive test detecting chronic pancreatitis. This prospective study enrolled… Expand
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Highly Cited
1995
Highly Cited
1995
OBJECTIVES Pancreatic elastase is highly stable along the intestinal tract. A new ELISA is commercially available to measure… Expand
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