Chymotrypsin-Like Elastase Family Member 1, human

Known as: Pancreatic Elastase 1, Elastase 1, Chymotrypsin-Like Elastase Family Member 1 
Chymotrypsin-like elastase family member 1 (258 aa, ~28 kDa) is encoded by the human CELA1 gene. This protein is involved in protein hydrolysis.
National Institutes of Health

Papers overview

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2012
2012
BACKGROUND Decreased function of the exocrine pancreas is frequent in patients with diabetes. Our aim was to investigate clinical… (More)
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2009
2009
OBJECTIVE Recently it has been shown that there is not only endocrine insufficiency in diabetic patients, but a frequent co… (More)
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2001
2001
BACKGROUND Previous studies suggested impaired pancreatic exocrine function in type I diabetes patients, but have been limited by… (More)
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2001
2001
BACKGROUND In patients with diarrhoea, faecal elastase-1 is used to detect exocrine pancreatic insufficiency. Diarrhoea is… (More)
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Highly Cited
2000
Highly Cited
2000
Reduced exocrine pancreatic function has been observed in a high percentage of patients with type 1 diabetes in the past. There… (More)
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2000
2000
Pancreatic elastase-1 (EL-1) is a specific human protease synthesised by the acinar cells. It is stable, unaffected by exogenous… (More)
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1999
1999
BACKGROUND The secretin-cholecystokinin (CCK) test is the gold standard in the evaluation of exocrine pancreatic insufficiency… (More)
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1998
1998
We studied potential indicators of severe acute pancreatitis by measuring the blood concentrations of various cytokines… (More)
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1997
1997
The simian virus 40 large T antigen induces tumors in a wide variety of tissues in transgenic mice, the precise tissues depending… (More)
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Highly Cited
1995
Highly Cited
1995
OBJECTIVES Pancreatic elastase is highly stable along the intestinal tract. A new ELISA is commercially available to measure… (More)
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