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Chymotrypsin-Like Elastase Family Member 1, human

Known as: Pancreatic Elastase 1, Elastase 1, Chymotrypsin-Like Elastase Family Member 1 
Chymotrypsin-like elastase family member 1 (258 aa, ~28 kDa) is encoded by the human CELA1 gene. This protein is involved in protein hydrolysis.
National Institutes of Health

Papers overview

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Review
2018
Review
2018
BACKGROUND & AIMS Tests to quantify fecal levels of chymotrypsin like elastase family member 3 (CELA3 or elastase‐1) in feces are… Expand
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Highly Cited
2012
Highly Cited
2012
Diabet. Med. 29, 1047–1054 (2012) 
Review
2011
Review
2011
Exocrine pancreatic disease is thought to be uncommon in clinical practice and usually secondary to excess alcohol intake… Expand
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Highly Cited
2004
Highly Cited
2004
OBJECTIVE To test the hypothesis that some patients with cystic fibrosis (CF) are misclassified as pancreatic insufficient, using… Expand
Highly Cited
2001
Highly Cited
2001
BACKGROUND Tubeless pancreatic function tests measuring the content of elastase-1 and the activity of chymotrypsin in stool are… Expand
Highly Cited
2000
Highly Cited
2000
Abstract Reduced exocrine pancreatic function has been observed in a high percentage of patients with type 1 diabetes in the past… Expand
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Highly Cited
1999
Highly Cited
1999
BACKGROUND The secretin-cholecystokinin (CCK) test is the gold standard in the evaluation of exocrine pancreatic insufficiency… Expand
Highly Cited
1997
Highly Cited
1997
Fecal elastase-1 is a candidate for a sensitive noninvasive test detecting chronic pancreatitis. This prospective study enrolled… Expand
Highly Cited
1995
Highly Cited
1995
OBJECTIVES Pancreatic elastase is highly stable along the intestinal tract. A new ELISA is commercially available to measure… Expand
Highly Cited
1992
Highly Cited
1992
A thorough analysis of the mechanism of inhibition of human leukocyte elastase (HLE) by a monocyclic beta-lactam and the… Expand