Chromosome Fragile Sites

Known as: Site, Chromosome Fragile, Fragile Sites, Chromosome, Sites, Chromosome Fragile 
Specific loci that show up during KARYOTYPING as a gap (an uncondensed stretch in closer views) on a CHROMATID arm after culturing cells under… (More)
National Institutes of Health

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Highly Cited
2011
Highly Cited
2011
Common fragile sites have long been identified by cytogeneticists as chromosomal regions prone to breakage upon replication… (More)
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Highly Cited
2009
Highly Cited
2009
Several inherited syndromes in humans are associated with cancer predisposition. The gene products defective in two of these… (More)
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Review
2008
Review
2008
Fragile sites are heritable specific chromosome loci that exhibit an increased frequency of gaps, poor staining, constrictions or… (More)
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Review
2007
Review
2007
Chromosomal fragile sites are specific loci that preferentially exhibit gaps and breaks on metaphase chromosomes following… (More)
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Highly Cited
2002
Highly Cited
2002
Conditions that partially inhibit DNA replication induce expression of common fragile sites. These sites form gaps and breaks on… (More)
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Highly Cited
1997
Highly Cited
1997
Drug-selected intrachromosomal gene amplification by breakage-fusion-bridge (BFB) cycles is well documented in mammalian cells… (More)
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Highly Cited
1996
Highly Cited
1996
A 200-300 kb region of chromosome 3p14.2, including the fragile site locus FRA3B, is homozygously deleted in multiple tumor… (More)
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Highly Cited
1991
Highly Cited
1991
Fragile X syndrome is the most frequent form of inherited mental retardation and is associated with a fragile site at Xq27.3. We… (More)
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Highly Cited
1988
Highly Cited
1988
Chromosomal fragile sites are points on chromosomes that usually appear as nonstaining chromosome or chromatid gaps. It has… (More)
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Review
1985
Review
1985
The fragile sites of human chromosomes are specific sites that are characterized by a tendency to show gaps, multiradial figures… (More)
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