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Chromosomal Gain

 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2018
Review
2018
Molecular insights turning game for management of ependymoma: A review of literature
Molecular biology of ependymoma is being extensively studied in recent years, providing insights into newer therapeutic… Expand
2015
2015
Integrated copy number and gene expression profiling analysis of epstein–barr virus‐positive diffuse large b‐cell lymphoma
Viral oncogenes and host immunosenescence have been suggested as causes of Epstein‐Barr virus‐positive diffuse large B‐cell… Expand
2014
2014
Targeted Inhibition of FAK, PYK2 and BCL-XL Synergistically Enhances Apoptosis in Ovarian Clear Cell Carcinoma Cell Lines
Ovarian clear cell carcinoma (OCCC) displays a higher resistance to first line chemotherapy, requiring the development of new… Expand
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2010
2010
Abstract 3130: Interacting protein of granulin-epithelin precursor in liver cancer
Proceedings: AACR 101st Annual Meeting 2010‐‐ Apr 17‐21, 2010; Washington, DC Background and Objective: Granulin-epithelin… Expand
2006
2006
Genome-wide semiquantitative microsatellite analysis of human hepatocellular carcinoma: discrete mapping of smallest region of overlap of recurrent chromosomal gains and losses.
Recurrent chromosomal gains at 1q, 6p, 8q, and 17q, or losses at 1p, 4q, 6q, 8p, 9p, 13q, 16q, and 17p are common features of… Expand
Highly Cited
2005
Highly Cited
2005
Inhibition of a new differentiation pathway in neuroblastoma by copy number defects of N-myc, Cdc42, and nm23 genes.
The best studied oncogenic mechanisms are inactivating defects in both alleles of tumor suppressor genes and activating mutations… Expand
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Highly Cited
2003
Highly Cited
2003
LIM kinase 1 is essential for the invasive growth of prostate epithelial cells: implications in prostate cancer.
Mammalian LIM kinase 1 (LIMK1) is involved in reorganization of actin cytoskeleton through inactivating phosphorylation of the… Expand
2002
2002
Identification of numerical chromosomal changes detected by interphase fluorescence in situ hybridization in high-grade prostate intraepithelial neoplasia as a predictor of carcinoma.
CONTEXT High-grade prostate intraepithelial neoplasia (HPIN) is the most likely precursor of prostate cancer. The condition of… Expand
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Highly Cited
2001
Highly Cited
2001
Frequent gain of copy number on the long arm of chromosome 3 in human cervical adenocarcinoma.
We analyzed genomic aberrations in 20 cervical adenocarcinomas by comparative genomic hybridization (CGH). Most tissue samples… Expand
2001
2001
Comparative genomic hybridization analysis identifies gains of 1p35 approximately p36 and chromosome 19 in osteosarcoma.
Osteosarcomas (OS) are aggressive tumors of the bone and often have a poor prognosis. Conventional cytogenetic analyses of OS… Expand
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