Chromatin Loop

Known as: Chromatin Loop Domains, DNA Loop 
A higher order chromatin structure above the level of the chromatin fiber. The organization of chromatin into loops permits the partitioning of… (More)
National Institutes of Health

Papers overview

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2017
2017
Folding of mammalian genomes into spatial domains is critical for gene regulation. The insulator protein CTCF and cohesin control… (More)
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2016
2016
Mammalian genes transcribe RNA not continuously, but in bursts. Transcriptional output can be modulated by altering burst… (More)
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Highly Cited
2014
Highly Cited
2014
The eukaryotic epigenome is shaped by the genome topology in three-dimensional space. Dynamic reversible variations in this… (More)
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Highly Cited
2008
Highly Cited
2008
The mechanism underlying enhancer-blocking by insulators is unclear. We explored the activity of human beta-globin HS5, the… (More)
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Highly Cited
2008
Highly Cited
2008
CTCF is a zinc finger DNA-binding protein that regulates the epigenetic states of numerous target genes. Using allelic regulation… (More)
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Review
2006
Review
2006
Recent studies of several multigene clusters have shown that gene activation by a remote enhancer is associated with chromatin… (More)
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Highly Cited
2005
Highly Cited
2005
Mutations in MECP2 are associated with Rett syndrome, an X-linked neurodevelopmental disorder. To identify genes targeted by… (More)
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Highly Cited
2005
Highly Cited
2005
Most of the transcription factors, RNA polymerases and enhancer binding factors are absent from condensed mitotic chromosomes. In… (More)
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Highly Cited
1998
Highly Cited
1998
Special AT-rich sequence-binding protein 1 (SATB1), a DNA-binding protein expressed predominantly in thymocytes, recognizes an… (More)
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1996
1996
At meiotic prophase, chromatin loops around a proteinaceous core, with the sizes of these loops varying between species… (More)
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