Chimeric antigen receptor

Known as: Artificial Antigen Receptor, CAR, Non-Native Antigen Receptor 
A cell-surface receptor that has been engineered to combine novel features and specificities from various sources in order to enhance its antigen… (More)
National Institutes of Health

Papers overview

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Review
2017
Review
2017
From autonomous cars and adaptive email-filters to predictive policing systems, machine learning (ML) systems are increasingly… (More)
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Review
2017
Review
2017
Chimeric antigen receptor (CAR) T cell therapy, together with checkpoint inhibition, has been celebrated as a breakthrough… (More)
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Review
2017
Review
2017
Pharmacological and cellular treatment of cancer is changing dramatically with benefits for patient outcome and comfort, but also… (More)
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Review
2016
Review
2016
Not finding a parking space for you sometimes is indeed a critical issue. The number of vehicles is also increasing daily adding… (More)
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Highly Cited
2015
Highly Cited
2015
BACKGROUND Chimeric antigen receptor (CAR) modified T cells targeting CD19 have shown activity in case series of patients with… (More)
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Highly Cited
2014
Highly Cited
2014
BACKGROUND Relapsed acute lymphoblastic leukemia (ALL) is difficult to treat despite the availability of aggressive therapies… (More)
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Highly Cited
2013
Highly Cited
2013
Chimeric antigen receptor-modified T cells with specificity for CD19 have shown promise in the treatment of chronic lymphocytic… (More)
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Highly Cited
2011
Highly Cited
2011
We designed a lentiviral vector expressing a chimeric antigen receptor with specificity for the B-cell antigen CD19, coupled with… (More)
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Highly Cited
2011
Highly Cited
2011
Targeted T cell immunotherapies using engineered T lymphocytes expressing tumor-directed chimeric antigen receptors (CARs) are… (More)
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Highly Cited
2010
Highly Cited
2010
In an attempt to treat cancer patients with ERBB2 overexpressing tumors, we developed a chimeric antigen receptor (CAR) based on… (More)
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