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Chemoprotective Agent

Known as: Chemoprotectants, Chemoprotective Drugs 
Chemicals which protect normal cells from the effects of chemotherapy.
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
This study was undertaken to evaluate the protective efficacy of the antioxidants vitamin E and Trolox (a water-soluble vitamin E… Expand
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Highly Cited
2005
Highly Cited
2005
Thiols such as N-acetylcysteine (NAC) are increasingly used in clinical trials of platinum chemotherapy as chemoprotectants. NAC… Expand
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Review
2004
Review
2004
Peripheral neuropathy is a major dose-limiting side effect of many chemotherapeutic agents. The type and degree of neuropathy… Expand
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2002
2002
Oltipraz, a synthetic derivative of the cruciferous vegetable product 1,2-dithiole-3-thione, is considered as one of the most… Expand
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Review
2002
Review
2002
Naphthalene is a bicyclic aromatic compound that has wide industrial and commercial applications. It is used as the starting… Expand
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Highly Cited
2001
Highly Cited
2001
Induction of phase 2 enzymes, which neutralize reactive electrophiles and act as indirect antioxidants, appears to be an… Expand
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Highly Cited
2001
Highly Cited
2001
BACKGROUND The induction of phase 2 enzymes by dithiolethiones such as oltipraz is an effective means for achieving protection… Expand
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Highly Cited
1995
Highly Cited
1995
The microcystins (Mcyst) are cyclic peptide hepatotoxins produced by cyanobacteria. They are chemically very stable and represent… Expand
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1991
1991
Microcystin-LR (MCLR) is a potent cyclic heptapeptide hepatotoxin produced by the blue-green algae, Microcystis aeruginosa. Toxic… Expand
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Highly Cited
1978
Highly Cited
1978
Part I: Drug Monographs. Analgesic and Anti-Inflammatory Drugs Antimigraine Drugs. Antomicrobial Drugs. Antineoplastics… Expand
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