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Cell Division Cycle Protein 20 Homolog

Known as: p55CDC 
Cell division cycle protein 20 homolog (499 aa, ~55 kDa) is encoded by the human CDC20 gene. This protein plays a role in metaphase arrest.
National Institutes of Health

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2005
2005
Taxol is widely used for the treatment of human cancer. Its mechanism of action in cells is dependent on drug concentration. At… Expand
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Highly Cited
2002
Highly Cited
2002
MAD2 is a key component of the spindle checkpoint that delays the onset of anaphase until all the kinetochores are attached to… Expand
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Highly Cited
2001
Highly Cited
2001
Mad1 was first identified in budding yeast as an essential component of the checkpoint system that monitors spindle assembly in… Expand
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Highly Cited
2000
Highly Cited
2000
Using combined immunofluorescence and fluorescence in situ hybridization (FISH) analysis we have extensively characterized the… Expand
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1999
1999
The mitotic checkpoint is thought to be essential for ensuring accurate chromosome segregation by implementing mitotic delay in… Expand
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Highly Cited
1998
Highly Cited
1998
We have investigated the function of p55CDC, a mammalian protein related to Cdc20 and Hct1/Cdh1 in Saccharomyces cerevisiae, and… Expand
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Highly Cited
1998
Highly Cited
1998
Activation of the mitotic checkpoint pathway in response to mitotic spindle damage in eukaryotic cells delays the exit from… Expand
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1997
1997
p55Cdc is a mammalian protein that shows high homology to the cell cycle proteins Cdc20p of Saccharomyces cerevisiae and the… Expand
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Highly Cited
1994
Highly Cited
1994
A novel protein, p55CDC, has been identified in cycling mammalian cells. This transcript is readily detectable in all… Expand
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