Cell Division Cycle Protein 20 Homolog

Known as: p55CDC 
Cell division cycle protein 20 homolog (499 aa, ~55 kDa) is encoded by the human CDC20 gene. This protein plays a role in metaphase arrest.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1994-2016
01219942016

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2016
2016
To ensure proper chromosome segregation, mitosis is tightly regulated by the spindle assembly checkpoint (SAC). Low… (More)
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Highly Cited
2008
Highly Cited
2008
The anaphase promoting complex (APC) or cyclosome is a multi-subunit E3 ubiquitin ligase. Cdc20 (fizzy (fzy)) or p55CDC, and Cdh1… (More)
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2006
2006
In a previous work, taking advantage of the gene-array screening technology, we analysed the effects of histone deacetylase (HDAC… (More)
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2005
2005
Taxol is widely used for the treatment of human cancer. Its mechanism of action in cells is dependent on drug concentration. At… (More)
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2005
2005
AIM To study the different gene expression profiles in rats with Barrett's esophagus (BE) and esophageal adenocarcinoma (EA… (More)
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2003
2003
The p55CDC (cell division cycle) protein is a key regulator of the cell cycle. p55CDC is related to both the CDC20 and the CDH1… (More)
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Highly Cited
2002
Highly Cited
2002
MAD2 is a key component of the spindle checkpoint that delays the onset of anaphase until all the kinetochores are attached to… (More)
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2000
2000
Eukaryotic cells have evolved a mechanism that delays the progression of mitosis until condensed chromosomes are properly… (More)
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Highly Cited
1998
Highly Cited
1998
We have investigated the function of p55CDC, a mammalian protein related to Cdc20 and Hct1/Cdh1 in Saccharomyces cerevisiae, and… (More)
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1994
1994
A novel protein, p55CDC, has been identified in cycling mammalian cells. This transcript is readily detectable in all… (More)
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