Casein Kinase Ikappa

RIG-I like receptors (RLRs) recognize cytosolic viral RNA and initiate innate immunity; they increase the production of type I… Expand

The pro-inflammatory cytokine interleukin-1 beta (IL-1 beta) plays critical roles in pathogenesis of osteoarthritis. Although… Expand

Nuclear factor kappaB (NF‐κB) plays an important role in the regulation of innate immune responses, apoptosis, inflammation, and… Expand

Epidemiological and experimental studies have suggested that high dietary intake of fats is associated with cognitive decline and… Expand

Expression of isolated beta integrin cytoplasmic domains in cultured endothelial cells was reported to induce cell detachment and… Expand

Hyperhomocysteinemia is an independent risk factor for the development of atherosclerosis. However, the underlying mechanism of… Expand

We have previously demonstrated that adenoviral gene transfer of the NF-κB inhibitor IκB to human islets results in protection… Expand

Control over the nuclear localization of nuclear factor κB/Rel proteins is accomplished in large part through association with… Expand

The IkappaB kinase (IKK) complex includes the catalytic components IKKalpha and IKKbeta in addition to the scaffold protein… Expand

Interleukin-1beta (IL-1beta) is a pro-inflammatory cytokine that inhibits beta cell function and promotes Fas-triggered apoptosis… Expand