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Carboxymethylenebutenolidase

Known as: 4-carboxymethylene but-2-enolide hydrolase, dienelactone hydrolase 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (1)

Carboxylic Ester Hydrolases
carboxymethylenebutenolidase activity

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2010
2010
Human Carboxymethylenebutenolidase as a Bioactivating Hydrolase of Olmesartan Medoxomil in Liver and Intestine
Olmesartan medoxomil (OM) is a prodrug type angiotensin II type 1 receptor antagonist widely prescribed as an antihypertensive… Expand
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1998
1998
Detoxification of protoanemonin by dienelactone hydrolase.
Protoanemonin is a toxic metabolite which may be formed during the degradation of some chloroaromatic compounds, such as… Expand
1993
1993
Substrate-induced activation of dienelactone hydrolase: an enzyme with a naturally occurring Cys-His-Asp triad.
The Cys-His-Asp catalytic triad found in dienelactone hydrolase (DLH) is unusual for several reasons. It has not been observed in… Expand
Highly Cited
1990
Highly Cited
1990
Refined structure of dienelactone hydrolase at 1.8 A.
The structure of dienelactone hydrolase (DLH) from Pseudomonus sp. B13, after stereochemically restrained least-squares… Expand
Highly Cited
1990
Highly Cited
1990
Different types of dienelactone hydrolase in 4-fluorobenzoate-utilizing bacteria.
Of various benzoate-utilizing bacteria tested, Alcaligenes eutrophus 335, A. eutrophus H16, A. eutrophus JMP222, A. eutrophus… Expand
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1989
1989
Degradation of p-chlorotoluene by a mutant of Pseudomonas sp. strain JS6.
Pseudomonas sp. strain JS6 grows on chlorobenzene, p-dichlorobenzene, or toluene as a sole source of carbon and energy. It does… Expand
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1988
1988
X-ray crystallographic structure of dienelactone hydrolase at 2.8 A.
The structure of dienelactone hydrolase, an enzyme of the beta-ketoadipate pathway, has been determined at 2.8 A resolution using… Expand
Highly Cited
1987
Highly Cited
1987
Nucleotide sequence and expression of clcD, a plasmid-borne dienelactone hydrolase gene from Pseudomonas sp. strain B13.
The clcD structural gene encodes dienelactone hydrolase (EC 3.1.1.45), an enzyme that catalyzes the conversion of dienelactones… Expand
1987
1987
Dienelactone hydrolase from Pseudomonas sp. strain B13.
Dienelactone hydrolase (EC 3.1.1.45) catalyzes the conversion of cis- or trans-4-carboxymethylenebut-2-en-4-olide (dienelactone… Expand
Highly Cited
1971
Highly Cited
1971
The metabolism of p-fluorobenzoic acid by a Pseudomonas sp.
A species of Pseudomonas previously used to study the degradation of p-fluorophenylacetic acid was used to investigate the… Expand
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