Camptosar

 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1997-2016
0102019972016

Papers overview

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Highly Cited
2009
Highly Cited
2009
Nonsteroidal anti-inflammatory drugs such as sulindac have shown promising antineoplastic activity, although toxicity from… (More)
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2008
2008
We determined whether the method used to encapsulate irinotecan into 1,2-distearoyl-sn-glycero-phosphocholine/cholesterol (DSPC… (More)
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2006
2006
Cancer cells differ from normal cells in their response to chemotherapy. We exploited this dissimilarity by identifying and… (More)
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2004
2004
SN-38, 7-ethyl-10-hydroxycamptothecin, is the active metabolite of Irinotecan (CPT-11), a topoisomerase I inhibitor commercially… (More)
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2004
2004
PURPOSE The dose-limiting toxicity of irinotecan (CPT-11; Camptosar) is delayed-onset diarrhea, with an incidence at the grade 3… (More)
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2003
2003
Chemotherapy has had limited success in biliary tract cancer. Of the newer agents, gemcitabine (Gemzar) and irinotecan (CPT-11… (More)
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Highly Cited
2002
Highly Cited
2002
Combining anticancer drugs with different mechanisms of action has the potential to enhance antitumor effect. CPT-11 (Camptosar… (More)
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2002
2002
We conducted a phase II study to assess the response rate and toxicity profile of the irinotecan (CPT-11, Camptosar) plus… (More)
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2002
2002
The hepatic metabolism and biliary secretion of irinotecan (CPT-11, Camptosar) and metabolites is complex and involves cytochrome… (More)
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1999
1999
Angiogenesis has been correlated with increased invasion and metastases in a variety of human neoplasms. Inadequate inhibition of… (More)
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