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Calcium Dobesilate

Known as: Dobesilate, Calcium, Benzenesulfonic acid, 2,5-dihydroxy-, calcium salt (2:1), Calcium Dobesilate [Chemical/Ingredient] 
A drug used to reduce hemorrhage in diabetic retinopathy.
National Institutes of Health

Related topics

Related topics

14 relations

Broader (4)

2,5-Dihydroxybenzenesulfonate2,5-Dihydroxybenzenesulfonic AcidDOBESILIC ACIDHemostatic Agents

Narrower (3)

Dexium Brand of Calcium DobesilateDoxiumdoxivenil gel
In Bloodagonistsanalogs & derivativesantagonists & inhibitors

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2019
Highly Cited
2019
Fabrication of resveratrol coated gold nanoparticles and investigation of their effect on diabetic retinopathy in streptozotocin induced diabetic rats.
Highly Cited
2010
Highly Cited
2010
Calcium Dobesilate Inhibits the Alterations in Tight Junction Proteins and Leukocyte Adhesion to Retinal Endothelial Cells Induced by Diabetes
OBJECTIVE Calcium dobesilate (CaD) has been used in the treatment of diabetic retinopathy in the last decades, but its mechanisms… 
Highly Cited
2006
Highly Cited
2006
Effect of calcium dobesilate on progression of early diabetic retinopathy: a randomised double-blind study
BackgroundThe study was carried out to confirm the effect of calcium dobesilate (CaD) compared to placebo (PLA) on the blood… 
Review
2004
Review
2004
Safety of Calcium Dobesilate in Chronic Venous Disease, Diabetic Retinopathy and Haemorrhoids
The aim of the present review is to consider the adverse effects and the safety profile of calcium dobesilate. Calcium dobesilate… 
Review
2004
Review
2004
Calcium Dobesilate for Chronic Venous Insufficiency: A Systematic Review
Chronic venous insufficiency (CVI) causes much discomfort and sick leave. Many randomized clinical trials (RCTs) have shown a… 
Highly Cited
2003
Highly Cited
2003
Diabetes impairs endothelium-dependent relaxation of human penile vascular tissues mediated by NO and EDHF.
2001
2001
Efficacy of calcium dobesilate in treating acute attacks of hemorrhoidal disease
PURPOSE: A randomized, double-blind, controlled study was conducted to investigate the efficacy of oral calcium dobesilate… 
Highly Cited
1999
Highly Cited
1999
CALCIUM DOBESILATE: PHARMACOLOGICAL PROFILE RELATED TO ITS USE IN DIABETIC RETINOPATHY
Calcium dobesilate (Doxium®) is used in the treatment of diabetic retinopathy. Clinical studies show a slowdown of the… 
Highly Cited
1998
Highly Cited
1998
In vitro antioxidant properties of calcium dobesilate
Summary— Calcium dobesilate, a vascular protective agent, was tested in vitro for its scavenging action against oxygen free… 
1988
1988
A Double-Blind Trial of Calcium Dobesilate in Chronic Venous Insufficiency
Calcium dobesilate was studied in a double-blind trial in 30 normal subjects and in 30 patients with chronic venous insufficiency… 
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