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Calcineurin inhibitor

Known as: Calcineurin Antagonists, Protein Phosphatase 2B Inhibitors, Calcineurin Blockers 
Compounds that inhibit or block the PHOSPHATASE activity of CALCINEURIN.
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
BACKGROUND The efficacy and safety of converting maintenance renal transplant recipients from calcineurin inhibitors (CNIs) to… Expand
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Highly Cited
2008
Highly Cited
2008
 
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Highly Cited
2003
Highly Cited
2003
BACKGROUND The calcineurin inhibitors cyclosporine (INN, cyclosporin) and tacrolimus have a narrow therapeutic index and show… Expand
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Highly Cited
2003
Highly Cited
2003
BACKGROUND Transplantation of nonrenal organs is often complicated by chronic renal disease with multifactorial causes. We… Expand
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Highly Cited
2003
Highly Cited
2003
BACKGROUND With improved immunosuppression and early allograft survival, chronic allograft nephropathy has become the dominant… Expand
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Review
2000
Review
2000
  • Wolf O Bechstein
  • Transplant international : official journal of…
  • 2000
  • Corpus ID: 28320458
Abstract Between 10 %–28 % of patients who receive the immunosuppressant cyclosporine (CsA) experience some form of neurotoxic… Expand
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Review
1999
Review
1999
Why are drugs such as cyclosporin A and FK506 effective and specific immunosuppressants when their target, calcineurin is present… Expand
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Highly Cited
1999
Highly Cited
1999
Skeletal muscle hypertrophy and regeneration are important adaptive responses to both physical activity and pathological stimuli… Expand
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Highly Cited
1998
Highly Cited
1998
Hypertrophic cardiomyopathy (HCM) is an inherited form of heart disease that affects 1 in 500 individuals. Here it is shown that… Expand
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Highly Cited
1994
Highly Cited
1994
LONG-TERM potentiation (LTP) is a synaptic mechanism thought to be involved in learning and memory1. Long-term depression (LTD… Expand
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