Calcineurin inhibitor

Known as: Calcineurin Antagonists, Protein Phosphatase 2B Inhibitors, Calcineurin Blockers 
Compounds that inhibit or block the PHOSPHATASE activity of CALCINEURIN.

Topic mentions per year

Topic mentions per year

1988-2018
020406019882018

Papers overview

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2012
2012
OBJECTIVE To describe the clinical course and outcome of 10 patients with Kawasaki disease (KD) treated with a calcineurin… (More)
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2011
2011
Calcineurin inhibitor (CNI) nephrotoxicity was recognized in Cambridge in the late 1970s. The vasoconstrictor impact of… (More)
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Highly Cited
2011
Highly Cited
2011
Calcineurin inhibitors (CNIs) are immunosuppressive drugs that are used widely to prevent rejection of transplanted organs and to… (More)
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Highly Cited
2010
Highly Cited
2010
Calcineurin inhibitors such as cyclosporin A (CsA) are the mainstay of immunosuppressive treatment for organ transplant… (More)
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2010
2010
In general, humoral immune responses depend critically upon T cell help. In transplantation, prevention or treatment of humoral… (More)
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2009
Highly Cited
2009
The Symphony study showed that at 1 year posttransplant, a regimen based on daclizumab induction, 2 g mycophenolate mofetil (MMF… (More)
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Highly Cited
2006
Highly Cited
2006
Calcineurin inhibitors have decreased acute rejection and improved early renal allograft survival, but their use has been… (More)
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Highly Cited
2006
Highly Cited
2006
BACKGROUND Immunosuppression in renal transplantation, although manageable in the short-term, is a major hurdle for long-term… (More)
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2005
2005
The use of calcineurin inhibitors in solid organ transplantation results in an increased risk of skin cancer. We examined the… (More)
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Highly Cited
2002
Highly Cited
2002
BACKGROUND Progressive nephrotoxicity caused by calcineurin inhibitor drugs contributes to the long-term decline in renal… (More)
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