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CYP7A1 gene

Known as: CYP7, cholesterol 7 alpha-monooxygenase, CHOLESTEROL 7-ALPHA-HYDROXYLASE 
This gene is involved in bile acid synthesis and steroid metabolism.
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
UNLABELLED Mouse fibroblast growth factor 15 (FGF15) and human ortholog FGF19 have been identified as the bile acid-induced… Expand
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Highly Cited
2007
Highly Cited
2007
Bile acid concentrations are controlled by a feedback regulatory pathway whereby activation of the farnesoid X receptor (FXR… Expand
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Highly Cited
2003
Highly Cited
2003
In rodent liver, transcription of the gene encoding cholesterol 7alpha-hydroxylase (CYP7A1), which catalyzes the rate-limiting… Expand
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Highly Cited
2002
Highly Cited
2002
The orphan nuclear hormone receptor SHP has been proposed to have a key role in the negative feedback regulation of bile acid… Expand
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Highly Cited
2002
Highly Cited
2002
Cholesterol 7 alpha-hydroxylase (CYP7A1) catalyzes the rate-limiting step in the classic pathway of bile acid biosynthesis… Expand
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Highly Cited
2001
Highly Cited
2001
Cholesterol 7α-hydroxylase (CYP7A1), the rate-limiting enzyme in the neutral pathway of bile acid biosynthesis, is feedback… Expand
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2001
2001
The initial and rate-limiting step in the classic pathway of bile acid biosynthesis is 7alpha-hydroxylation of cholesterol, a… Expand
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Highly Cited
2001
Highly Cited
2001
The cholesterol 7alpha-hydroxylase gene (CYP7A1) plays an important role in regulation of bile acid biosynthesis and cholesterol… Expand
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Highly Cited
2000
Highly Cited
2000
Cholesterol 7α-hydroxylase gene (CYP7A1) transcription is repressed by bile acids. The goal of this study is to elucidate the… Expand
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Highly Cited
2000
Highly Cited
2000
In the studies reported herein, we show that two complementary experimental models: inbred strains of mice (i.e. C57BL/6 and C3H… Expand
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