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CYP2D8P gene

Known as: CYP2D8P, ccytochrome P450 family 2 subfamily D member 8, pseudogene 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Pharmacogenetic Variation in Over 100 Genes in Patients Receiving Acenocumarol
Coumarins are widely prescribed worldwide, and in Mexico acenocumarol is the preferred form. It is well known that despite its… 
2015
2015
Molecular Evolution of the CYP2D Subfamily in Primates: Purifying Selection on Substrate Recognition Sites without the Frequent or Long-Tract Gene Conversion
The human cytochrome P450 (CYP) 2D6 gene is a member of the CYP2D gene subfamily, along with the CYP2D7P and CYP2D8P pseudogenes… 
2011
2011
Evolution of the CYP2D gene cluster in humans and four non-human primates.
The human cytochrome P450 2D6 (CYP2D6) is a primary enzyme involved in the metabolism of about 25% of commonly used therapeutic… 
2009
2009
Expression and Functional Analysis of CYP2D6.24, CYP2D6.26, CYP2D6.27, and CYP2D7 Isozymes
The objectives of this study were to compare the drug-metabolizing activity of human CYP2D6.24 (I297L), CYP2D6.26 (I369T), and… 
Highly Cited
2005
Highly Cited
2005
Determination of CYP2D6 gene copy number by pyrosequencing.
BACKGROUND Identification of CYP2D6 alleles *5 (deletion of the whole CYP2D6 gene) and *2xN (gene duplication) is very important… 
2005
2005
COMMENT ON “A FRAMESHIFT MUTATION AND ALTERNATE SPLICING IN HUMAN BRAIN GENERATE A FUNCTIONAL FORM OF THE PSEUDOGENE CYTOCHROME P4502D7 THAT DEMETHYLATES CODEINE TO MORPHINE”
The polymorphic enzyme CYP2D6 is important for the metabolism of many clinically used drugs and contributes to the large patient… 
2001
2001
The CYP 2 D 6 Humanized Mouse : Effect of the Human CYP 2 D 6 Transgene and HNF 4 on the Disposition of Debrisoquine in the Mouse
CYP2D6 is a highly polymorphic human gene responsible for a large variability in the disposition of more than 100 drugs to which… 
Highly Cited
1989
Highly Cited
1989
The human debrisoquine 4-hydroxylase (CYP2D) locus: sequence and identification of the polymorphic CYP2D6 gene, a related gene, and a pseudogene.
The debrisoquine-4-hydroxylase polymorphism is a genetic variation in oxidative drug metabolism characterized by two phenotypes… 
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