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CYP2D8P gene
Known as:
CYP2D8P
, ccytochrome P450 family 2 subfamily D member 8, pseudogene
National Institutes of Health
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Pharmacogenetic Variation in Over 100 Genes in Patients Receiving Acenocumarol
V. González-Covarrubias
,
Javier Ureña-Carrion
,
+5 authors
X. Soberón
Frontiers in Pharmacology
2017
Corpus ID: 22128249
Coumarins are widely prescribed worldwide, and in Mexico acenocumarol is the preferred form. It is well known that despite its…
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2015
2015
Molecular Evolution of the CYP2D Subfamily in Primates: Purifying Selection on Substrate Recognition Sites without the Frequent or Long-Tract Gene Conversion
Y. Yasukochi
,
Y. Satta
Genome Biology and Evolution
2015
Corpus ID: 354800
The human cytochrome P450 (CYP) 2D6 gene is a member of the CYP2D gene subfamily, along with the CYP2D7P and CYP2D8P pseudogenes…
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2011
2011
Evolution of the CYP2D gene cluster in humans and four non-human primates.
Y. Yasukochi
,
Y. Satta
Genes & Genetic Systems
2011
Corpus ID: 21078896
The human cytochrome P450 2D6 (CYP2D6) is a primary enzyme involved in the metabolism of about 25% of commonly used therapeutic…
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2009
2009
Expression and Functional Analysis of CYP2D6.24, CYP2D6.26, CYP2D6.27, and CYP2D7 Isozymes
Wei-Yan Zhang
,
Youbin Tu
,
R. Haining
,
A. Yu
Drug Metabolism And Disposition
2009
Corpus ID: 10581229
The objectives of this study were to compare the drug-metabolizing activity of human CYP2D6.24 (I297L), CYP2D6.26 (I369T), and…
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Highly Cited
2005
Highly Cited
2005
Determination of CYP2D6 gene copy number by pyrosequencing.
E. Söderbäck
,
A. Zackrisson
,
B. Lindblom
,
A. Alderborn
Clinical Chemistry
2005
Corpus ID: 10428277
BACKGROUND Identification of CYP2D6 alleles *5 (deletion of the whole CYP2D6 gene) and *2xN (gene duplication) is very important…
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2005
2005
COMMENT ON “A FRAMESHIFT MUTATION AND ALTERNATE SPLICING IN HUMAN BRAIN GENERATE A FUNCTIONAL FORM OF THE PSEUDOGENE CYTOCHROME P4502D7 THAT DEMETHYLATES CODEINE TO MORPHINE”
J. Hoskins
,
S. Marsh
,
H. McLeod
Drug Metabolism And Disposition
2005
Corpus ID: 10857188
The polymorphic enzyme CYP2D6 is important for the metabolism of many clinically used drugs and contributes to the large patient…
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2001
2001
The CYP 2 D 6 Humanized Mouse : Effect of the Human CYP 2 D 6 Transgene and HNF 4 on the Disposition of Debrisoquine in the Mouse
J. Corchero
,
C. Granvil
,
+5 authors
F. Gonzalez
2001
Corpus ID: 20989688
CYP2D6 is a highly polymorphic human gene responsible for a large variability in the disposition of more than 100 drugs to which…
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Highly Cited
1989
Highly Cited
1989
The human debrisoquine 4-hydroxylase (CYP2D) locus: sequence and identification of the polymorphic CYP2D6 gene, a related gene, and a pseudogene.
S. Kimura
,
M. Umeno
,
R. Skoda
,
U. Meyer
,
F. Gonzalez
American Journal of Human Genetics
1989
Corpus ID: 25077007
The debrisoquine-4-hydroxylase polymorphism is a genetic variation in oxidative drug metabolism characterized by two phenotypes…
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