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CYP2C11 protein, rat

Known as: cytochrome P-450 2C11, cytochrome P-450 CYP2C11, rat, male-specific, CYP2C11 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (3)

Aryl Hydrocarbon HydroxylasesCytochrome P450 Family 2Steroid 16-alpha-Hydroxylase

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Drug metabolism enzymes in a steatotic model of rat treated with a high fat diet and a low dose of streptozotocin.
2014
2014
Rhythmic expression of cytochrome P450 epoxygenases CYP4x1 and CYP2c11 in the rat brain and vasculature.
Mammals have circadian variation in blood pressure, heart rate, vascular tone, thrombotic tendency, and cerebral blood flow (CBF… 
2012
2012
Combined Contributions of Impaired Hepatic CYP2C11 and Intestinal Breast Cancer Resistance Protein Activities and Expression to Increased Oral Glibenclamide Exposure in Rats with Streptozotocin…
The purpose of this study was to evaluate the contributions of impaired cytochrome P450 and breast cancer resistance protein… 
Highly Cited
2010
Highly Cited
2010
Age-related changes in hepatic expression and activity of cytochrome P450 in male rats
Age-related changes in hepatic expression and activity of cytochrome P450 (CYP) were investigated in male rats aged 3 (weanling… 
2008
2008
Induction of several cytochrome P450 genes by doxorubicin in H9c2 cells.
2006
2006
Rat Cytochrome P450 2C11 in Liver Microsomes Involved in Oxidation of Anesthetic Agent Propofol and Deactivated by Prior Treatment with Propofol
Propofol (2,6-diisopropylphenol) is a widely-used anesthetic agent attributable to its rapid biotransformation. Liver microsomal… 
Highly Cited
2003
Highly Cited
2003
Endocrine disruptors induce cytochrome P450 by affecting transcriptional regulation via pregnane X receptor.
2003
2003
Regulation of CYP2C11 by dehydroepiandrosterone and peroxisome proliferators: identification of the negative regulatory region of the gene.
Treatment of rats with peroxisome proliferators is known to affect gene expression, including suppression of CYP2C11. The current… 
2002
2002
In vitro biotransformation of sildenafil (Viagra) in the male rat: the role of CYP2C11.
To assess the suitability of the male rat model for human studies on sildenafil metabolism, we examined the biotransformation of… 
Highly Cited
1998
Highly Cited
1998
In vivo cimetidine inhibits hepatic CYP2C6 and CYP2C11 but not CYP1A1 in adult male rats.
We previously reported that in vivo cimetidine inhibits hepatic microsomal enzyme activities mediated by cytochrome P450 (CYP… 
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