CXCR4 protein, human

Known as: LAP-3, CXC-R4, Lipopolysaccharide-Associated Protein 3 
C-X-C chemokine receptor type 4 (352 aa, ~40 kDa) is encoded by the human CXCR4 gene. This protein is involved in the stimulation of mitogenic… (More)
National Institutes of Health

Papers overview

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Review
2010
Review
2010
Chemokines, small proinflammatory chemoattractant cytokines that bind to specific G-protein-coupled seven-span transmembrane… (More)
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Highly Cited
2009
Highly Cited
2009
The stromal cell-derived factor-1/CXCL12 chemokine engages the CXCR4 and CXCR7 receptors and regulates homeostatic and pathologic… (More)
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Highly Cited
2006
Highly Cited
2006
In the bone marrow, the special microenvironment niches nurture a pool of hematopoietic stem cells (HSCs). Many HSCs reside near… (More)
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Review
2004
Review
2004
Malignant cells from at least 23 different types of cancer express the chemokine receptor CXCR4 and respond to its ligand CXCL12… (More)
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Highly Cited
2004
Highly Cited
2004
The chemokine receptor CXCR4 and its cognate ligand CXCL12 recently have been proposed to regulate the directional trafficking… (More)
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Highly Cited
2003
Highly Cited
2003
The vast majority of brain tumors in adults exhibit glial characteristics. Brain tumors in children are diverse: Many have… (More)
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Highly Cited
2001
Highly Cited
2001
Ligand-induced trafficking plays an important role in the physiologic regulation of many G protein-coupled receptors (GPCRs… (More)
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Highly Cited
1998
Highly Cited
1998
Chemokines and their receptors are important in cell migration during inflammation, in the establishment of functional lymphoid… (More)
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Highly Cited
1998
Highly Cited
1998
Vascularization of organs generally occurs by remodelling of the preexisting vascular system during their differentiation and… (More)
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Highly Cited
1998
Highly Cited
1998
The bicyclam AMD3100 (formula weight 830) blocks HIV-1 entry and membrane fusion via the CXCR4 co-receptor, but not via CCR5… (More)
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