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CXCR4 Inhibitor

An antagonist of the C-X-C chemokine receptor type 4 (CXCR4). CXCR4, which belongs to the G protein-coupled receptor (GPCR) gene family, plays an… 
National Institutes of Health

Papers overview

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2017
2017
CXCR4 Inhibitor Active in Clear Cell RCC
Combination treatment with a novel CXCR4 inhibitor and axitinib resulted in an encouraging overall response rate and disease… 
2017
2017
CXCR 4 / RhoA signaling pathway is involved in miR-128-regulated proliferation and apoptosis of human thyroid cancer cells
microRNA-128 (miR-128), a kind of short, noncoding RNAs, functioned as a tumor marker. However, the underlying function and… 
2013
2013
Non-Drug HIV Entry Inhibitors Using a CXCR 4 Selective Synthetic Peptide , DV 3 : Binding Affinity and Evaluation of Drug Delivery Potential
SUMMARY Peptide conjugates comprising multiple DV3 sequences (1, 2 and 4 copies of LGASWHRPDK) were designed and synthesized to… 
2010
2010
CXCR4 inhibitor plerixafor and G-CSF allow for an effective peripheral blood stem cell collection in patients who failed previous mobilization attempt
Background: Plerixafor is a CXCR4 receptor inhibitor, which was recently introduced for stem cell mobilization in myeloma and… 
2004
2004
Anti-HIV activity profile of a novel CCR5 inhibitor, AMD887, in combination with the CXCR4 inhibitor AMD070
2003
2003
The anti-HIV activity of the CXCR4 inhibitor AMD3100 is independent of the CXCR4/HIV coreceptor level