FAQ

CXCR2-transduced Autologous Tumor Infiltrating Lymphocytes

Known as: CXCR2-transduced Autologous TILs 
A preparation of autologous tumor infiltrating lymphocytes (TILs) that are transduced, ex vivo, with a retroviral vector encoding a gene for CXC… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1997-2015
0119972015

Related topics

Related topics

4 relations
Antigen SensitizationCytotoxic T-LymphocytesT-Cell Activationimmunopotentiation

Related mentions per year

Related mentions per year

1971-2018
197019801990200020102020
CXCR2-transduced Autologous Tumor Infiltrating Lymphocytes
Cytotoxic T-Lymphocytes
T-Cell Activation
immunopotentiation
Antigen Sensitization

Papers overview

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2015
2015
LAG-3 and 4-1BB identify dysfunctional antigen-specific T cells in the tumor microenvironment and combinatorial LAG-3/4-1BB targeting gives synergistic tumor control
Although the presence of tumor-infiltrating lymphocytes (TILs) indicates an endogenous anti-tumor response, immune regulatory… (More)
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2012
2012
Analysis of Vδ1 T cells in clinical grade melanoma-infiltrating lymphocytes
γδ T cells, including Vδ1 and Vδ2 T cells, can recognize tumor-associated ligands neglected by conventional αβ T cells in a MHC… (More)
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2008
2008
Adoptive cell therapy for patients with melanoma, using tumor-infiltrating lymphocytes genetically engineered to secrete interleukin-2.
Adoptive cell transfer of tumor-infiltrating lymphocytes (TILs) after lymphodepletion mediates regression in 50% of patients with… (More)
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2006
2006
Targeted in vivo expression of IFN-gamma-inducible protein 10 induces specific antitumor activity.
Although it is known that the chemoattractant effect of IFN-gamma inducible protein 10 (IP-10), a CXC chemokine (CXCL10), plays… (More)
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1997
1997
Defective granzyme B gene expression and lytic response in T lymphocytes infiltrating human renal cell carcinoma.
Granzyme B is a protein thought to play a pivotal role in the cytolytic functions of T cells. In view of this, the inducibility… (More)
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