CXCR2-transduced Autologous Tumor Infiltrating Lymphocytes
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Tumours from multiple cancer types can be infiltrated by CD8þ T cells (TILs) (Spranger et al, 2016). TILs are thought to be… Expand mune system cells that identify and kill infected and cancerous cells. After recognizing and attaching to a target cell, CL cells… Expand The immune response plays an important role in staving off cancer; however, mechanisms of immunosuppression hinder productive… Expand Heterogeneous cell populations form an interconnected network that determine their collective output. One example of such a… Expand Adoptive cell transfer of tumor-infiltrating lymphocytes (TILs) after lymphodepletion mediates regression in 50% of patients with… Expand OBJECTIVE
The aim of the study was to determine the impact of tumor-infiltrating lymphocytes on survival in patients with… Expand Although it is known that the chemoattractant effect of IFN-gamma inducible protein 10 (IP-10), a CXC chemokine (CXCL10), plays… Expand