CX3CR1 protein, human

Known as: Chemokine, CX3C Motif, Receptor 1, CMKBRL1 protein, human, Beta Chemokine Receptor-Like 1 
CX3C chemokine receptor 1 (355 aa, ~40 kDa) is encoded by the human CX3CR1 gene. This protein plays a role in cell adhesion, chemotaxis, cell defense… (More)
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2011
Highly Cited
2011
Aberrant microglial activation has been proposed to contribute to the cognitive decline in Alzheimer disease (AD), but the… (More)
  • table 1
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2010
Highly Cited
2010
Microglia, the immune cells of the brain, can have a beneficial effect in Alzheimer's disease by phagocytosing amyloid-β. Two… (More)
  • figure 1
Is this relevant?
Highly Cited
2008
Highly Cited
2008
CX3CR1 (fractalkine receptor) is important for sustaining normal microglial activity in the brain. Lack of CX3CR1 reportedly… (More)
Is this relevant?
Highly Cited
2007
Highly Cited
2007
The role of retinal microglial cells (MCs) in age-related macular degeneration (AMD) is unclear. Here we demonstrated that all… (More)
  • table 1
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2006
Highly Cited
2006
Microglia, the resident inflammatory cells of the CNS, are the only CNS cells that express the fractalkine receptor (CX3CR1… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 5
  • table 1
Is this relevant?
Highly Cited
2004
Highly Cited
2004
Fractalkine is a unique chemokine reported to be constitutively expressed by neurons. Its only receptor, CX3CR1, is expressed by… (More)
Is this relevant?
Highly Cited
2003
Highly Cited
2003
BACKGROUND Chemokines are important mediators of inflammatory cell recruitment that play a significant role in atherosclerosis… (More)
  • table 1
  • figure 2
  • figure 1
  • table 2
  • figure 3
Is this relevant?
Highly Cited
2001
Highly Cited
2001
Fractalkine, a chemokine expressed by inflamed endothelium, induces leukocyte adhesion and migration via the receptor CX3CR1, and… (More)
  • table 1
  • table 2
  • table 3
  • figure 1
  • figure 2
Is this relevant?
Highly Cited
2000
Highly Cited
2000
The seven-transmembrane receptor CX(3)CR1 is a specific receptor for the novel CX(3)C chemokine fractalkine (FKN) (neurotactin… (More)
Is this relevant?
Highly Cited
1998
Highly Cited
1998
Fractalkine is a multimodular human leukocyte chemoattractant protein and a member of the chemokine superfamily. Unlike other… (More)
Is this relevant?