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CV 5975
Known as:
CV-5975
National Institutes of Health
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1 relation
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Thiazepines
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1988
1988
(R)-3-[(S)-1-carboxy-5-(4-piperidyl)pentyl]amino-4-oxo-2,3,4,5- tetrahydro-1,5-benzothiazepine-5-acetic acid (CV-5975): a new potent and long-lasting inhibitor of angiotensin converting enzyme.
Y. Inada
,
K. Itoh
,
K. Kamiya
,
H. Sugihara
,
K. Nishikawa
Japanese Journal of Pharmacology
1988
Corpus ID: 35585485
The synthetic design and the biological activities of structurally new angiotensin converting enzyme (ACE) inhibitors, (R)-3…
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1988
1988
Antihypertensive action of a new angiotensin converting enzyme inhibitor, (R)-3-[(S)-1-carboxy-5-(4-piperidyl)pentyl]amino-4-oxo-2,3,4,5-tetr ahy dro-1,5-benzothiazepine-5-acetic acid (CV-5975), in…
Y. Inada
,
M. Tanabe
,
K. Kawazoe
,
K. Nishikawa
Japanese Journal of Pharmacology
1988
Corpus ID: 41451854
The antihypertensive activity of a new angiotensin converting enzyme (ACE) inhibitor, CV-5975, (R)-3-[(S)-1-carboxy-5-(4…
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1987
1987
An improved synthesis of the new angiotensin converting enzyme inhibitor CV-5975 via a chemoenzymatic process.
M. Kori
,
K. Itoh
,
H. Sugihara
Chemical and pharmaceutical bulletin
1987
Corpus ID: 39658179
A chemoenzymatic synthesis of the new angiotensin converting enzyme inhibitor CV-5975 (1) is described. The optically active key…
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