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CRYAB protein, human

Known as: RF protein, human, Heat Shock Protein Beta-5, crystallin, alpha B protein, human 
Alpha-crystallin B chain (175 aa, ~20 kDa) is encoded by the human CRYAB gene. This protein is involved in the stabilization of lens proteins.
National Institutes of Health

Related topics

Related topics

9 relations
CRYAB geneHeat shock proteinsLens, CrystallineNegative Regulation of Cell Death

Broader (1)

alpha-Crystallin B Chain

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2018
Review
2018
Small Heat Shock Proteins, Amyloid Fibrils, and Nicotine Stimulate a Common Immune Suppressive Pathway with Implications for Future Therapies.
The α7 nicotinic acetylcholine receptor (α7nAChR) is central to the anti-inflammatory function of the vagus nerve in a… 
2017
2017
Chaperone-like activity of synthetic polyanions can be higher than the activity of natural chaperones at elevated temperature.
2017
2017
Identification of highly connected hub genes in the protective response program of human macrophages and microglia activated by alpha B‐crystallin
The glial stress protein alpha B‐crystallin (HSPB5) is an endogenous agonist for Toll‐like receptor 2 in CD14+ cells. Following… 
Review
2014
Review
2014
Positive or Negative Involvement of Heat Shock Proteins in Multiple Sclerosis Pathogenesis: An Overview
Abstract Multiple sclerosis (MS) is the most diffuse chronic inflammatory disease of the central nervous system. Both immune… 
2013
2013
Structure and properties of chimeric small heat shock proteins containing yellow fluorescent protein attached to their C-terminal ends
Recombinant chimeras of small heat shock proteins (sHsp) HspB1, HspB5, and HspB6 containing enhanced yellow fluorescent protein… 
2013
2013
Reaction of small heat-shock proteins to different kinds of cellular stress in cultured rat hippocampal neurons
Upregulation of small heat-shock proteins (sHsps) in response to cellular stress is one mechanism to increase cell viability. We… 
Review
2012
Review
2012
Mechanisms in the development of multiple sclerosis lesions: reconciling autoimmune and neurodegenerative factors.
Both immune-mediated and neurodegenerative processes play a role in the pathogenesis of multiple sclerosis (MS). There is still… 
2011
2011
Chaperone Activity of α B-Crystallin Is Responsible for Its Incorrect Assignment as an Autoantigen in Multiple Sclerosis
For 15 y, α B-crystallin (heat shock protein [Hsp] B5) has been labeled an autoantigen in multiple sclerosis (MS) based on… 
Review
2010
Review
2010
Versatility of the small heat shock protein HSPB6 (Hsp20)
The recently published review by Dreiza et al. (Cell Stress and Chaperones DOI 10.1007/s12192-0090127-8) dealing with the… 
Review
2008
Review
2008
HspB5/alphaB-crystallin: properties and current progress in neuropathy.
HspB5/alphaB-crystallin (alphaBC), one of the most representative member of mammalian small heat shock protein family (sHsp… 
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