CRISPR-Cas Systems

Known as: CRISPR Cas Systems, Systems, CRISPR-Cas, System, CRISPR-Cas 
Adaptive antiviral defense mechanisms, in archaea and bacteria, based on DNA repeat arrays called CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC… (More)
National Institutes of Health

Papers overview

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Review
2017
Review
2017
Bacteria and archaea are engaged in a constant arms race to defend against the ever-present threats of viruses and invasion by… (More)
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Review
2017
Review
2017
The bacterial and archaeal CRISPR-Cas systems of adaptive immunity show remarkable diversity of protein composition, effector… (More)
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Highly Cited
2015
Highly Cited
2015
The microbial adaptive immune system CRISPR mediates defense against foreign genetic elements through two classes of RNA-guided… (More)
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Highly Cited
2015
Highly Cited
2015
Microbial CRISPR-Cas systems are divided into Class 1, with multisubunit effector complexes, and Class 2, with single protein… (More)
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Review
2014
Review
2014
Targeted genome editing using engineered nucleases has rapidly gone from being a niche technology to a mainstream method used by… (More)
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Review
2014
Review
2014
The CRISPR-Cas systems of archaeal and bacterial adaptive immunity are classified into three types that differ by the repertoires… (More)
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Highly Cited
2013
Highly Cited
2013
Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) and CRISPR-associated (Cas) systems in bacteria and archaea… (More)
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Highly Cited
2013
Highly Cited
2013
Genome editing of model organisms is essential for gene function analysis and is thus critical for human health and agricultural… (More)
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Highly Cited
2013
Highly Cited
2013
To the Editor: CRISPR-Cas systems have been developed as an efficient gene editing technology in cells and model organisms. Here… (More)
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Review
2011
Review
2011
Bacteria and archaea have evolved defense and regulatory mechanisms to cope with various environmental stressors, including virus… (More)
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