CPU0213
National Institutes of Health
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Objectives Abnormal vascular activity in diabetes is related not only to impaired nitric oxide bioavailability but also to…
Background/Aims: NADPH oxidase(NOX) is the main source of reactive oxygen species (ROS) in diabetic nephropathy (DN). Activation…
An increase in reactive oxygen species (ROS) through NADPH oxidase activation frequently follows stress that activates…
1 The aims of the present study were to examine whether: (i) upregulation of the endothelin (ET) pathway is involved in…
AbstractAim:The downregulation of phospholamban (PLB) and FKBP12.6 as a result of β-receptor activation is involved in the…
Arrhythmias correlate with disorders of either K(2+) channels in sarcolemma or calcium modulating system in sarcoplasmic…
The depressed sarcoplasmic reticulum (SR) Ca2+-ATPase (SERCA2a) and Ca2+-release channels (ryanodine receptor RyR2) are involved…
AbstractAim:To examine whether a novel endothelin receptor antagonist, CPU0213, is effective in relieving the acute renal failure…