FAQ

CPSF1 gene

Known as: cleavage and polyadenylation specific factor 1, CLEAVAGE-POLYADENYLATION SPECIFICITY FACTOR, 160-KD SUBUNIT, CPSF160 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

2004-2016
012320042016

Papers overview

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2017
2017
Genome-wide association study for lactation persistency, female fertility, longevity, and lifetime profit index traits in Holstein dairy cattle.
Female fertility in Holstein cattle can decline when intense genetic selection is placed on milk production. One approach to… (More)
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2017
2017
Targeting cleavage and polyadenylation specific factor 1 via shRNA inhibits cell proliferation in human ovarian cancer
Cleavage and polyadenylation specificity factor 1 (CPSF1), a member of CPSF complex, has been reported to play a key role in pre… (More)
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2015
2015
Position-specific binding of FUS to nascent RNA regulates mRNA length.
More than half of all human genes produce prematurely terminated polyadenylated short mRNAs. However, the underlying mechanisms… (More)
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2014
2014
Reconstitution of CPSF active in polyadenylation: recognition of the polyadenylation signal by WDR33.
Cleavage and polyadenylation specificity factor (CPSF) is the central component of the 3' processing machinery for polyadenylated… (More)
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2014
2014
CPSF30 and Wdr33 directly bind to AAUAAA in mammalian mRNA 3' processing.
AAUAAA is the most highly conserved motif in eukaryotic mRNA polyadenylation sites and, in mammals, is specifically recognized by… (More)
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2013
2013
Cleavage and polyadenylation specificity factor 1 (CPSF1) regulates alternative splicing of interleukin 7 receptor (IL7R) exon 6.
Interleukin 7 receptor, IL7R, is expressed exclusively on cells of the lymphoid lineage, and its expression is crucial for the… (More)
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2013
2013
3'-End processing of histone pre-mRNAs in Drosophila: U7 snRNP is associated with FLASH and polyadenylation factors.
3'-End cleavage of animal replication-dependent histone pre-mRNAs is controlled by the U7 snRNP. Lsm11, the largest component of… (More)
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2012
2012
Investigating Alternative Splicing and Polyadenylation of the Interleukin 7 Receptor ( IL 7 R ) Exon 6 : Implications for Multiple Sclerosis
Investigating Alternative Splicing and Polyadenylation of the Interleukin 7 Receptor (IL7R) exon 6: Implications for Multiple… (More)
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2009
2009
A core complex of CPSF73, CPSF100, and Symplekin may form two different cleavage factors for processing of poly(A) and histone mRNAs.
Metazoan histone mRNAs are unique: their pre-mRNAs contain no introns, and the mRNAs are not polyadenylated, ending instead in a… (More)
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Highly Cited
2004
Highly Cited
2004
Human Fip1 is a subunit of CPSF that binds to U-rich RNA elements and stimulates poly(A) polymerase.
In mammals, polyadenylation of mRNA precursors (pre-mRNAs) by poly(A) polymerase (PAP) depends on cleavage and polyadenylation… (More)
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