CPG-ODN

Known as: CpG Oligodeoxynucleotide, CpG-28, CpG-28 Oligodeoxynucleotide 
A synthetic oligodeoxynucleotide, containing unmethylated CpG motifs derived from bacterial DNA, with immunostimulatory activities. A CpG… (More)
National Institutes of Health

Papers overview

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Review
2009
Review
2009
Toll-like receptor 9 (TLR9) agonists have demonstrated substantial potential as vaccine adjuvants, and as mono- or combination… (More)
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Highly Cited
2005
Highly Cited
2005
The induction of potent CD8+ T cell responses by vaccines to fight microbes or tumors remains a major challenge, as many… (More)
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Highly Cited
2004
Highly Cited
2004
Oligodeoxynucleotides (ODN) with unmethylated deoxycytidyl-deoxyguanosine (CpG) dinucleotides (CpG ODN) mimic the… (More)
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Highly Cited
2004
Highly Cited
2004
DNA containing unmethylated cytidyl guanosyl (CpG) sequences, which are underrepresented in mammalian genomes but prevalent in… (More)
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Highly Cited
2002
Highly Cited
2002
The Toll-like receptor (TLR)9 is critical for the recognition of immunostimulatory CpG motifs but may cooperate with other TLRs… (More)
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Highly Cited
2001
Highly Cited
2001
The immature plasmacytoid dendritic cell (PDC) is identical with the principal type I IFN-producing cell upon viral infection… (More)
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Highly Cited
1998
Highly Cited
1998
Bacterial DNA and immunostimulatory (i.s.) synthetic CpG-oligodeoxynucleotides (ODN) act as adjuvants for Th1 responses and… (More)
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Highly Cited
1998
Highly Cited
1998
Unmethylated CpG motifs in bacterial DNA, plasmid DNA and synthetic oligodeoxynucleotides (CpG ODN) activate dendritic cells (DC… (More)
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Highly Cited
1997
Highly Cited
1997
Synthetic oligodeoxynucleotides (ODN) that contain unmethylated CpG motifs (CpG ODN) induce macrophages to secrete IL-12, which… (More)
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Highly Cited
1997
Highly Cited
1997
Recent advances in our understanding of the immune response are allowing for the logical design of new approaches to cancer… (More)
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