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CP-4055

Known as: 4-amino-1-[5-O-[(9E)-octadec-9-enoyl]-beta-D-arabinofuranosyl]pyrimidin-2(1H)-one, CP 4055, CP4055 
The lipophilic 5'-elaidic acid ester of the deoxycytidine analog cytosine arabinoside (cytarabine; Ara-C) with potential antineoplastic activity. As… Expand
National Institutes of Health

Papers overview

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2013
2013
Elacytarabine (formerly CP-4055) is a lipid-conjugated derivative of the nucleoside analog cytarabine. Elacytarabine was… Expand
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2011
2011
SummaryCytarabine (ara-C) and gemcitabine (dFdC) are commonly used anticancer drugs, which depend on the equilibrative (ENT) and… Expand
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2011
2011
PurposeTreatment of patients with recurrent ovarian cancer remains a challenge, and there is a need for new and more effective… Expand
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2010
2010
The deoxynucleoside analogs cytarabine (Ara-C) and gemcitabine (dFdC) are widely used in the treatment of cancer. Due to their… Expand
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2010
2010
To bypass resistance due to limited entry into the cell derivatives of cytarabine (CP-4055, elacytarabine) and gemcitabine (CP… Expand
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2010
2010
The clinical activity of pyrimidine analogues (araC and gemcitabine) is impaired by different mechanisms of resistance and… Expand
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2009
2009
Purpose. Cytarabine (ara-C) has limited activity in solid tumours. CP-4055 (ELACYT™) is a novel ara-C-5’-elaidic acid ester that… Expand
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2008
2008
This study evaluated combination drug partners for CP-4055, the C18:1Δ9,trans unsaturated fatty acid ester of cytarabine in HL-60… Expand
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Highly Cited
2004
Highly Cited
2004
1-beta-D-arabinofuranosylcytosine (ara-C) is a deoxycytidine analog with activity in leukemia, which requires phosphorylation by… Expand
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