CP-4055

Known as: 4-amino-1-[5-O-[(9E)-octadec-9-enoyl]-beta-D-arabinofuranosyl]pyrimidin-2(1H)-one, CP 4055, CP4055 
The lipophilic 5'-elaidic acid ester of the deoxycytidine analog cytosine arabinoside (cytarabine; Ara-C) with potential antineoplastic activity. As… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

2004-2012
02420042012

Papers overview

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2013
2013
Elacytarabine (formerly CP-4055) is a lipid-conjugated derivative of the nucleoside analog cytarabine. Elacytarabine was… (More)
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2012
2012
elacytarabine CIV in the dose range 875--2000mg/m per day may allow more flexible administration and dosing than for ara-C. AUC… (More)
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2011
2011
Cytarabine (ara-C) and gemcitabine (dFdC) are commonly used anticancer drugs, which depend on the equilibrative (ENT) and… (More)
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2010
2010
The deoxynucleoside analogs cytarabine (Ara-C) and gemcitabine (dFdC) are widely used in the treatment of cancer. Due to their… (More)
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2010
2010
To bypass resistance due to limited entry into the cell derivatives of cytarabine (CP-4055, elacytarabine) and gemcitabine (CP… (More)
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2010
2010
The clinical activity of pyrimidine analogues (araC and gemcitabine) is impaired by different mechanisms of resistance and… (More)
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2009
2009
PURPOSE Cytarabine (ara-C) has limited activity in solid tumours. CP-4055 (ELACYT) is a novel ara-C-5'-elaidic acid ester that… (More)
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2008
2008
This study evaluated combination drug partners for CP-4055, the C18:1(Delta9,trans) unsaturated fatty acid ester of cytarabine in… (More)
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2006
2006
2067 Background: CP-4055 (ELACYT, ara-C 5'-elaidic acid ester) is a novel cytotoxic agent with broad preclinical antitumor… (More)
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2004
2004
1-beta-D-arabinofuranosylcytosine (ara-C) is a deoxycytidine analog with activity in leukemia, which requires phosphorylation by… (More)
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