COP9 signalosome

Known as: COP9 complex, COP9 complex location, CSN 
A protein complex that catalyzes the deneddylation of proteins, including the cullin component of SCF ubiquitin E3 ligase; deneddylation increases… (More)
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2011
2011
BACKGROUND Autophagy is essential to intracellular homeostasis and is involved in the pathophysiology of a variety of diseases… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Review
2003
Review
2003
The COP9 signalosome (CSN) is composed of eight distinct subunits and is highly homologous to the lid sub-complex of the 26S… (More)
  • table 1
  • figure 2
  • table 2
  • figure 1
  • figure 3
Is this relevant?
Review
2003
Review
2003
COP9 Signalosome (CSN) is a fascinating protein complex whose biochemical and physiological functions are only beginning to be… (More)
  • figure 1
  • figure 2
  • table 1
Is this relevant?
Highly Cited
2003
Highly Cited
2003
Nucleotide excision repair (NER) is a major cellular defense against the carcinogenic effects of ultraviolet light from the sun… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2003
Highly Cited
2003
The COP9 signalosome (CSN) is an evolutionarily conserved, nucleus-enriched multiprotein complex. CSN plays roles in… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • table 1
Is this relevant?
Review
2003
Review
2003
The COP9 signalosome (CSN) is a highly conserved protein complex implicated in diverse biological functions that involve… (More)
  • figure 1
Is this relevant?
Highly Cited
2003
Highly Cited
2003
The signalosome is implicated in regulating cullin-dependent ubiquitin ligases. We find that two signalosome subunits, Csn1 and… (More)
Is this relevant?
Highly Cited
2002
Highly Cited
2002
The fifth component of the COP9 signalosome complex, Jab1/CSN5, directly binds to and induces specific down-regulation of the… (More)
Is this relevant?
Highly Cited
2001
Highly Cited
2001
SCF ubiquitin ligases control various processes by marking regulatory proteins for ubiquitin-dependent proteolysis. To illuminate… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2001
Highly Cited
2001
In higher eukaryotic cells, the p53 protein is degraded by the ubiquitin-26S proteasome system mediated by Mdm2 or the human… (More)
Is this relevant?