Skip to search formSkip to main contentSkip to account menu

CNGA1 gene

Known as: CNCG1, CYCLIC NUCLEOTIDE-GATED CHANNEL, PHOTORECEPTOR, cGMP-GATED, 1, cyclic nucleotide gated channel alpha 1 
National Institutes of Health

Related topics

Related topics

1 relation
RETINITIS PIGMENTOSA 49

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2014
Highly Cited
2014
Whole Exome Analysis Identifies Frequent CNGA1 Mutations in Japanese Population with Autosomal Recessive Retinitis Pigmentosa
Objective The purpose of this study was to investigate frequent disease-causing gene mutations in autosomal recessive retinitis… 
2013
2013
Multiple mechanisms underlying rectification in retinal cyclic nucleotide-gated (CNGA1) channels
In cyclic nucleotide‐gated (CNGA1) channels, in the presence of symmetrical ionic conditions, current–voltage (I‐V) relationship… 
2009
2009
Mutations reveal voltage gating of CNGA1 channels in saturating cGMP
Activity of cyclic nucleotide–gated (CNG) cation channels underlies signal transduction in vertebrate visual receptors. These… 
2009
2009
Conformational rearrangements in the S6 domain and C-linker during gating in CNGA1 channels
This work completes previous findings and, using cysteine scanning mutagenesis (CSM) and biochemical methods, provides detailed… 
2004
2004
Autosomal recessive retinitis pigmentosa in a Pakistani family mapped to CNGA1 with identification of a novel mutation.
PURPOSE To map the locus for autosomal recessive retinitis pigmentosa in a large Pakistani family and to determine the causative… 
2002
2002
Novel homozygous mutation in the alpha subunit of the rod cGMP gated channel (CNGA1) in two Spanish sibs affected with autosomal recessive retinitis pigmentosa
Retinitis pigmentosa (RP, MIM 268000) comprises a clinically and genetically heterogeneous group of disorders leading to… 
Highly Cited
1997
Highly Cited
1997
Cloning and widespread distribution of the rat rod-type cyclic nucleotide-gated cation channel.
We used Northern blot analysis, ribonuclease protection assay (RPA), reverse transcriptase-polymerase chain reaction, and in situ… 
1997
1997
Molecular cloning of cyclic nucleotide-gated cation channel subunits from rat pineal gland.
Review
1995
Review
1995
Molecular diversity of cyclic nucleotide-gated cation channels
Cyclic nucleotide-gated cation channels (CNG channels) form a multi-gene family consisting of at least five distinct members… 
Highly Cited
1992
Highly Cited
1992
Human rod photoreceptor cGMP-gated channel: amino acid sequence, gene structure, and functional expression
Phototransduction in retinal rods involves a G-protein-mediated signaling cascade that leads to cGMP hydrolysis and the closure… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)