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CMP-N-acetylneuraminate monooxygenase activity

Known as: CMP-N-acetylneuraminic acid hydroxylase activity, cytidine-5'-monophosphate-N-acetylneuraminic acid hydroxylase activity, CMP-Neu5Ac hydroxylase activity 
Catalysis of the reaction: CMP-N-acetylneuraminate + NADPH + H+ + O2 = CMP-N-glycoloylneuraminate + NADP+ + H2O. [EC:]
National Institutes of Health

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In order to investigate the mode of interaction between the N-quarternized cytosine base and the aromatic amino acid, the crystal… Expand
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