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Background: The operon structure of the C. elegans genome was used to identify functional interaction partners for the chloride… Expand The volume‐regulating protein, ICln, interacts with the conserved KxGFFKR α‐integrin signature motif. ICln is an abundant protein… Expand ICln is a ubiquitously expressed multifunctional protein that plays a critical role in regulatory volume decrease after cell… Expand The many different functional phenotypes described in mammalian cells can only be explained by an intense interaction of the… Expand A critical role for the conserved alpha-integrin cytoplasmic motif, KVGFFKR, is recognized in the regulation of activation of the… Expand ICln is a multifunctional protein that is essential for cell volume regulation. It can be found in the cytosol and is associated… Expand Abstract Cell volume expansion stimulates the efflux of solutes, including the amino acid taurine, to accomplish a regulatory… Expand pICln is a protein that induces an outwardly rectifying, nucleotide-sensitive chloride current (ICln) when expressed in Xenopus… Expand 1. Phenotypical similarities between ICl,swell, the cell‐swelling‐induced chloride current and ICln, the nucleotide‐sensitive… Expand ICln is a cloned chloride channel paramount for regulatory volume decrease. Two different loci that carry the coding region for… Expand