FAQ

CLCN6 gene

Known as: CHLORIDE CHANNEL 6, Chloride Channel, Voltage-Sensitive 6 Gene, CLC6 
This gene plays a role in chloride ion transport.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1987-2017
012319872017

Related topics

Related topics

6 relations
Chloride Transport Protein 6Homo sapiensIonophore activityLigand Binding
(More)

Related mentions per year

Related mentions per year

1937-2018
19401960198020002020
CLCN6 gene
Ligand Binding
Transmembrane Transport
Homo sapiens
Molecular Transport
Ionophore activity

Papers overview

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2010
2010
The late endosomal ClC-6 mediates proton/chloride countertransport in heterologous plasma membrane expression.
Members of the CLC protein family of Cl(-) channels and transporters display the remarkable ability to function as either… (More)
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2010
2010
Genetic architecture of ambulatory blood pressure in the general population: insights from cardiovascular gene-centric array.
Genetic determinants of blood pressure are poorly defined. We undertook a large-scale, gene-centric analysis to identify loci and… (More)
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2010
2010
Chloride channels and transporters in human corneal epithelium.
Transport of water and electrolytes is critical for corneal clarity. Recent studies indicate another important function of… (More)
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2006
2006
Intracellular localization of ClC chloride channels and their ability to form hetero-oligomers.
ClC chloride channels (ClCs) can be classified into two groups in terms of their cellular localizations: ClCs present in the… (More)
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2000
2000
The human and mouse methylenetetrahydrofolate reductase (MTHFR) genes: genomic organization, mRNA structure and linkage to the CLCN6 gene.
Methylenetetrahydrofolate reductase (MTHFR), a pivotal enzyme in folate metabolism, regulates the proportional distribution of… (More)
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1999
1999
Complete genomic structure of the CLCN6 and CLCN7 putative chloride channel genes(1).
The CLC family of voltage-gated chloride channels comprises nine members in mammals. CLCN6 and CLCN7 belong to a novel, poorly… (More)
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1997
1997
Expression of human pICln and ClC-6 in Xenopus oocytes induces an identical endogenous chloride conductance.
pICln is a protein that induces an outwardly rectifying, nucleotide-sensitive chloride current (ICln) when expressed in Xenopus… (More)
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Highly Cited
1996
Highly Cited
1996
A family of putative chloride channels from Arabidopsis and functional complementation of a yeast strain with a CLC gene disruption.
We have cloned four novel members of the CLC family of chloride channels from Arabidopsis thaliana. The four plant genes are… (More)
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Highly Cited
1995
Highly Cited
1995
ClC-6 and ClC-7 are two novel broadly expressed members of the CLC chloride channel family.
We cloned two novel members of the CLC chloride channel family from rat and human brain. ClC-6 is a 97-kDa protein, and ClC-7 a… (More)
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Highly Cited
1987
Highly Cited
1987
The regulatory c1 locus of Zea mays encodes a protein with homology to myb proto-oncogene products and with structural similarities to transcriptional activators.
The structure of the wild-type c1 locus of Zea mays was determined by sequence analysis of one genomic and two cDNA clones. The… (More)
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