CIITA gene

Known as: CLASS II TRANSACTIVATOR, nucleotide-binding oligomerization domain, leucine rich repeat and acid domain containing, NLR family, acid domain containing 
This gene plays a role in transcriptional regulation.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1973-2017
0204019732017

Papers overview

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Highly Cited
2011
Highly Cited
2011
Chromosomal translocations are critically involved in the molecular pathogenesis of B-cell lymphomas, and highly recurrent and… (More)
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Highly Cited
2010
Highly Cited
2010
We performed a second-generation genome-wide association study of 4,533 individuals with celiac disease (cases) and 10,750… (More)
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Highly Cited
2001
Highly Cited
2001
Cell surface expression of major histocompatibility complex class II (MHCII) molecules is increased during the maturation of… (More)
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Highly Cited
2001
Highly Cited
2001
We present here an in vivo view of major histocompatibility complex (MHC) class II promoter assembly, nucleosome modifications… (More)
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Highly Cited
2000
Highly Cited
2000
Inhibitors of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase, or statins, are effective lipid-lowering agents… (More)
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Highly Cited
2000
Highly Cited
2000
By virtue of its control over major histocompatibility complex class II (MHC-II) gene expression, CIITA represents a key molecule… (More)
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Highly Cited
2000
Highly Cited
2000
Scaffold molecules interact with multiple effectors to elicit specific signal transduction pathways. CIITA, a non-DNA-binding… (More)
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Highly Cited
1996
Highly Cited
1996
CIITA activates the expression of multiple genes involved in antigen presentation and it is believed to be required for both… (More)
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Highly Cited
1995
Highly Cited
1995
CIITA, a gene that can complement a transcriptional mutation of the major histocompatibility complex (MHC) class II genes, was… (More)
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Highly Cited
1994
Highly Cited
1994
The class II transactivator (CIITA) has been shown to be required for major histocompatibility complex (MHC) class II gene… (More)
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