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CK2 is a ubiquitously expressed, constitutively active Ser/Thr protein kinase, which is considered the most pleiotropic protein… Expand CK2 genes are overexpressed in many human cancers, and most often overexpression is associated with worse prognosis. Site… Expand OBJECTIVES
Casein kinase 2 (CK2) is overexpressed in several types of cancer. It has more than 300 substrates mainly involved in… Expand CIGB-300 is a novel clinical-stage synthetic peptide that impairs the casein kinase 2 (CK2)-mediated phosphorylation of B23… Expand Chronic lymphocytic leukemia (CLL) remains an incurable malignancy, urging for the identifcation of new molecular targets for… Expand CK2 represents an oncology target scientifically validated. However, clinical research with inhibitors of the CK2-mediated… Expand CIGB-300 is a proapoptotic peptide-based drug that abrogates the CK2-mediated phosphorylation. This peptide has antineoplastic… Expand CIGB-300, formerly known as P15-tat, is a proapoptotic peptide with established antiproliferative activity in vitro and… Expand Protein Kinase CK2 is a serine-threonine kinase frequently deregulated in many human tumors. Here, we hypothesized that a peptide… Expand BackgroundCervical cancer is now considered the second leading cause of death among women worldwide, and its incidence has… Expand