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CI 966

Known as: CI-966 
 
National Institutes of Health

Papers overview

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2005
2005
In a recent study, EF1502 [N-[4,4-bis(3-methyl-2-thienyl)-3-butenyl]-3-hydroxy-4-(methylamino)-4,5,6,7-tetrahydrobenzo [d… Expand
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2001
2001
On the basis of the SAR of a series of known gamma-aminobutyric acid (GABA) uptake inhibitors, including 4 (SKF 89976), new… Expand
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Highly Cited
1997
Highly Cited
1997
Ganaxolone (CCD 1042) is a 3b-methyl-substituted analog of the endogenous neuroactive steroid 3a-hydroxy-5a-pregnan20-one… Expand
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1995
1995
1. Cerebral ischemia of 5 min duration was induced in unanesthetized gerbils by bilateral occlusion of the carotid arteries. 2… Expand
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Highly Cited
1994
Highly Cited
1994
gamma-Aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain. The synaptic action of GABA is… Expand
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1994
1994
gamma-Aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian central nervous system. Molecular… Expand
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1994
1994
The discriminative stimulus effects of indirect-acting GABAergic drugs were compared to those of pentobarbital (PB) and midazolam… Expand
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1993
1993
Single-dose administration of 50 mg of 1-[2-[bis[4- (trifluoromethyl)phenyl]methoxy]ethyl]-1,2,5,6-tetrahydro-3… Expand
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1993
1993
CI-966 exhibits anticonvulsant properties in various animal models. The drug acts by inhibiting synaptic uptake of γ-aminobutyric… Expand
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1990
1990
A new potent, blood-brain barrier permeable gamma-aminobutyric acid (GABA) uptake blocker, 1-[2-[bis[4-(trifluoromethyl)-phenyl… Expand
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