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CI 1011

Known as: CI-1011 
National Institutes of Health

Papers overview

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2010
2010
Cerebral accumulation of amyloid-&bgr; (A&bgr;) is characteristic of Alzheimer disease and of amyloid precursor protein (APP… Expand
2007
2007
The objective of the present study was to determine whether a novel acyl-CoA:cholesterol acyltransferase (ACAT) inhibitor… Expand
Review
2003
Review
2003
Avasimibe is a novel orally bioavailable ACAT inhibitor, currently under clinical development (phase III trials). It was safe… Expand
2002
2002
Acyl-CoA:cholesterol acyltransferase (ACAT) inhibitors have been shown to reduce atherosclerotic lesions in animals; however, the… Expand
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2002
2002
We have studied the cellular and molecular mechanisms involved in the suppression of apoB secretion from HepG2 cells following… Expand
1999
1999
The concept that hepatic cholesteryl ester (CE) mass and the rate of cholesterol esterification regulate hepatocyte assembly and… Expand
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Highly Cited
1998
Highly Cited
1998
The hypocholesterolemic and anti-atherogenic properties of sulfamic acid ((2,4,6-tris (1-methylethyl) phenyl) acetyl) 2,6-bis(1… Expand
1998
1998
Lipoprotein(a) (Lp(a)), which is generated through the covalent association of apolipoprotein(a) (apo(a)) and apo B-100-LDL, is… Expand
1998
1998
A liquid chromatographic/mass spectrometric (LC/MS/MS) method to quantitate CI-1011 in rat plasma has been validated and compared… Expand