CI 1011

Known as: CI-1011 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1996-2009
02419962009

Papers overview

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2010
2010
Cerebral accumulation of amyloid-beta (Abeta) is characteristic of Alzheimer disease and of amyloid precursor protein (APP… (More)
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2007
2007
The objective of the present study was to determine whether a novel acyl-CoA:cholesterol acyltransferase (ACAT) inhibitor… (More)
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Review
2003
Review
2003
Avasimibe is a novel orally bioavailable ACAT inhibitor, currently under clinical development (phase III trials). It was safe… (More)
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2003
2003
This study assessed the efficacy and safety of avasimibe (CI-1011), an inhibitor of acyl coenzyme A-cholesterol acyltransferase… (More)
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2002
2002
Acyl-CoA:cholesterol acyltransferase (ACAT) inhibitors have been shown to reduce atherosclerotic lesions in animals; however, the… (More)
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2002
2002
We have studied the cellular and molecular mechanisms involved in the suppression of apoB secretion from HepG2 cells following… (More)
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2001
2001
Although acyl-CoA:cholesterol acyltransferase (ACAT) inhibitors have been shown to reduce lipid levels in several animal models… (More)
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1999
1999
The concept that hepatic cholesteryl ester (CE) mass and the rate of cholesterol esterification regulate hepatocyte assembly and… (More)
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1998
1998
The hypocholesterolemic and anti-atherogenic properties of sulfamic acid ((2,4,6-tris (1-methylethyl) phenyl) acetyl) 2,6-bis(1… (More)
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1998
1998
Lipoprotein(a) (Lp(a)), which is generated through the covalent association of apolipoprotein(a) (apo(a)) and apo B-100-LDL, is… (More)
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